Tyrosinase-Related Protein 1 Protein (TYRP1) (His tag)
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- 抗原 See all Tyrosinase-Related Protein 1 (TYRP1) 蛋白
- Tyrosinase-Related Protein 1 (TYRP1)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Tyrosinase-Related Protein 1 protein is labelled with His tag.
- 原理
- Recombinant Human TRP1/TYRP1 Protein (Human Cells, His Tag)
- 序列
- Met 1- Arg 471
- 产品特性
- A DNA sequence encoding the human TYRP1 (P17643) extracellular domain (Met 1- Arg 471) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TYRP1 蛋白
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Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) protein (GST tag)
TYRP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Tyrosinase-Related Protein 1 (TYRP1) (AA 25-477) protein (His tag)Crystallography grade TYRP1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Tyrosinase-Related Protein 1 (TYRP1) (AA 25-477) protein (His tag)Crystallography grade TYRP1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Tyrosinase-Related Protein 1 (TYRP1) (AA 25-537) protein (rho-1D4 tag)Crystallography grade TYRP1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Tyrosinase-Related Protein 1 (TYRP1) (AA 25-537) protein (rho-1D4 tag)Crystallography grade TYRP1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Tyrosinase-Related Protein 1 (TYRP1) (AA 82-333), (partial) protein (GST tag)TYRP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Tyrosinase-Related Protein 1 (TYRP1) protein (Myc-DYKDDDDK Tag)TYRP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Tyrosinase-Related Protein 1 (TYRP1)
- 别名
- /TYRP1 (TYRP1 产品)
- 别名
- CAS2 Protein, CATB Protein, GP75 Protein, OCA3 Protein, TRP Protein, TRP1 Protein, TYRP Protein, b-PROTEIN Protein, LOC397853 Protein, Trypsin Protein, hm:zeh0659 Protein, tyrp1 Protein, zgc:100893 Protein, B Protein, TYRP1 Protein, tyrp-1 Protein, TRP-1 Protein, Tyrp Protein, b Protein, brown Protein, isa Protein, tyrosinase related protein 1 Protein, protease, serine 1 L homeolog Protein, tyrosinase-related protein 1b Protein, tyrosinase-related protein 1 Protein, tyrosinase-related protein 1 L homeolog Protein, tyrosinase-related protein 1a Protein, TYRP1 Protein, prss1.L Protein, tyrp1b Protein, Tyrp1 Protein, tyrp1.L Protein, tyrp1 Protein, LOC100136490 Protein, tyrp-1 Protein, tyrp1a Protein
- 背景
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Background: Tyrosinase-related protein 1, also known as TYRP1 or TRP1, is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Mutations in this enzyme are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. TYRP1 / TRP1 is involved in the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. This enzyme may regulate or influence the type of melanin synthesized. The expression of Tyrosinase-related protein 1 (TYRP1) is regulated by the microphthalmia-associated transcription factor (MITF). There is mounting evidence demonstrating that in addition to its role in eumelanin synthesis, TYRP1 is involved in maintaining stability of tyrosinase proliferation and melanocyte cell death.
Synonym: b-PROTEIN,CAS2,CATB,GP75,OCA3,TRP,TRP1,TYRP
- 分子量
- 52.2 kDa
- UniProt
- P17643
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