TWSG1 Protein (His tag)
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- 抗原 See all TWSG1 蛋白
- TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This TWSG1 protein is labelled with His tag.
- 原理
- Recombinant Mouse TWSG1/TSG Protein (His Tag)
- 序列
- Met 1-Phe 222
- 产品特性
- A DNA sequence encoding the mouse TWSG1 (Q9EP52) (Met 1-Phe 222) was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 93 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product TWSG1 蛋白
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Twisted Gastrulation Homolog 1 (TWSG1) (AA 1-223) protein (GST tag)
TWSG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Twisted Gastrulation Homolog 1 (TWSG1) (AA 124-223) protein (GST tag)TWSG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))
- 别名
- TWSG1/TSG (TWSG1 产品)
- 别名
- TWSG1 Protein, TSG Protein, DKFZp469J051 Protein, 1810013J15Rik Protein, 9030422N06Rik Protein, AW552143 Protein, D17Ertd403e Protein, Tsg Protein, Twg Protein, fi23f01 Protein, tsg Protein, tsga Protein, twsg1 Protein, wu:fi23f01 Protein, twsg Protein, tsg1 Protein, tsgb Protein, ztsg1 Protein, twisted gastrulation BMP signaling modulator 1 Protein, twisted gastrulation homolog 1 (Drosophila) Protein, twisted gastrulation BMP signaling modulator 1a Protein, twisted gastrulation BMP signaling modulator 1 S homeolog Protein, twisted gastrulation BMP signaling modulator 1 L homeolog Protein, twisted gastrulation BMP signaling modulator 1b Protein, TWSG1 Protein, Twsg1 Protein, twsg1a Protein, twsg1.S Protein, twsg1.L Protein, twsg1b Protein
- 背景
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Background: TWSG1 belongs to the twisted gastrulation protein family. TWSG1 from different species are functionally equivalent. In contrast to Drosophila where TWSG1 expression is limited to early embryos, expression of TWSG1 is found throughout mouse and human development. Mutations in the TWSG1 gene cause at least some of the cells on the dorsal half of the embryo to adopt more ventral cell fates. This is thought to involve gradients of the signaling molecule decapentaplegic. TWSG1 may function as a bone morphogenetic protein signalling agonist or antagonize these activities. It can dislodge latent bone morphogenetic proteins and thus provides a permissive signal that allows high BMP signaling in the embryo. TWSG1 is a cofactor in the antagonism of chordin to BMP signaling. It also binds both the vertebrate Decapentaplegic ortholog BMP4 and chordin and forms ternary complexes. Meanwhile, TWSG1 increases binding of chordin to BMP4, potentiates the ability of chordin to induce secondary axes in Xenopus embryos, and enhances chordin cleavage by vertebrate proteases related to tolloid at a site poorly used in the absence of TWSG1. The presence of TWSG1 enhances the secondary axis-inducing activity of 2 products of chordin cleavage.
Synonym: 1810013J15Rik,9030422N06Rik,AW552143,D17Ertd403e,Tsg,Twg
- 分子量
- 23.6kDa
- UniProt
- Q9EP52
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