TACSTD2 Protein (His tag)
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- 抗原 See all TACSTD2 蛋白
- TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This TACSTD2 protein is labelled with His tag.
- 原理
- Recombinant Mouse TROP2/TACSTD2 Protein (His Tag)(Active)
- 序列
- Met 1-Gln 270
- 产品特性
- A DNA sequence encoding the extracellular domain of mouse TACSTD2 (Q8BGV3?) (Met 1-Gln 270) was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 92 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells.When 5 x 10E4 cells/well are added to TACSTD2-coated plates (40 μg/mL, 100 μL/well), > 50% cells will adhere after 1 hour at 37°C.
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- Discover our top product TACSTD2 蛋白
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Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 27-274) protein (His tag)
TACSTD2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) protein (His tag)TACSTD2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 27-274) protein (His-Avi Tag,Biotin)TACSTD2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (Active) protein (His tag)TACSTD2 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) protein (His tag)TACSTD2 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (Active) protein (Fc Tag)TACSTD2 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) protein (His tag)TACSTD2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) protein (Fc Tag)TACSTD2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (Active) protein (His tag)TACSTD2 宿主: 猕猴 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) protein (mFc-His Tag)TACSTD2 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
- 别名
- TROP2/TACSTD2 (TACSTD2 产品)
- 别名
- EGP-1 Protein, EGP1 Protein, GA733-1 Protein, GA7331 Protein, GP50 Protein, M1S1 Protein, TROP2 Protein, C80403 Protein, Ly97 Protein, Prp1 Protein, tumor associated calcium signal transducer 2 Protein, tumor-associated calcium signal transducer 2 Protein, TACSTD2 Protein, Tacstd2 Protein
- 背景
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Background: TROP-2, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little or no expression of Trop-2 in adult somatic tissue. Because it is a cell surface protein that is selectively expressed in tumor cells, Trop-2 is a potential therapeutic target. The cytoplasmic tail of Trop-2 possesses potential serine and tyrosine phosphorylation sites and a phosphatidyl-inositol binding consensus sequence. Trop-2 transduces an intracellular calcium signal, are consistent with the hypothesis that it acts as a cell surface receptor and support a search for a physiological ligand. TROP2 encoding by an intronless gene was originally defined by the monoclonal antibody GA733, and is a member of a family of at least two type I membrane proteins. The other known member is GA733-2, also called EpCAM and TROP1. It has been suggested by studies that the GA733-1 gene was formed by the retroposition of the GA733-2 gene via an mRNA intermediate.
Synonym: Tumor-associated calcium signal transducer 2,Tacstd2,Trop2,Cell surface glycoprotein Trop-2, TROP-2,C80403,EGP-1,GA733-1,Ly97
- 分子量
- 29.4 kDa
- UniProt
- Q8BGV3
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