Tryptophan Hydroxylase 2 Protein (TPH2) (His tag)
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- 抗原 See all Tryptophan Hydroxylase 2 (TPH2) 蛋白
- Tryptophan Hydroxylase 2 (TPH2)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Tryptophan Hydroxylase 2 protein is labelled with His tag.
- 原理
- Recombinant Human TPH2 Protein (His Tag)
- 序列
- Met 1-Ile496
- 产品特性
- Recombinant Human Tryptophan 5-Hydroxylase 2 is produced by our E.coli expression system and the target gene encoding Met1-Ile496 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TPH2 蛋白
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Tryptophan Hydroxylase 2 (TPH2) (AA 151-466) protein (His tag)
TPH2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Tryptophan Hydroxylase 2 (TPH2) (AA 1-490) protein (Strep Tag)Crystallography grade TPH2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Tryptophan Hydroxylase 2 (TPH2) (AA 1-488) protein (Strep Tag)Crystallography grade TPH2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Tryptophan Hydroxylase 2 (TPH2) protein (Myc-DYKDDDDK Tag)TPH2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- Tryptophan Hydroxylase 2 (TPH2)
- 别名
- TPH2 (TPH2 产品)
- 别名
- ADHD7 Protein, NTPH Protein, Ntph Protein, tphR Protein, wu:fq15a04 Protein, AU043594 Protein, tryptophan hydroxylase 2 Protein, tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) Protein, TPH2 Protein, Tph2 Protein, tph2 Protein
- 背景
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Background: Tryptophan 5-hydroxylase 2 (TPH2) is an isozyme member of the biopterin-dependent aromatic amino acid hydroxylase family. TPH2 is primarily expressed in the serotonergic neurons of the brain, with the highest expression found in the raphe nucleus of the midbrain. TPH2 catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Genetic variation in TPH2 may influence susceptibility to major depressive disorder (MDD). Defects in TPH2 are the cause of psychiatric diseases such as bipolar affective disorder and major depression.
Synonym: Tryptophan 5-Hydroxylase 2, Neuronal Tryptophan Hydroxylase, Tryptophan 5-Monooxygenase 2, TPH2, NTPH
- 分子量
- 58.8 kDa
- UniProt
- Q14CC5
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