TREML2 Protein (His tag)
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- 抗原 See all TREML2 蛋白
- TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This TREML2 protein is labelled with His tag.
- 原理
- Recombinant Human TREML2/TLT2 Protein (His Tag)
- 序列
- Met 1-Ser 268
- 产品特性
- A DNA sequence encoding the human TREML2 (NP_079083.2) extracellular domain (Met 1-Ser 268) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TREML2 蛋白
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Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 25-270) protein (His tag)
TREML2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 19-268) protein (His tag)TREML2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 19-268) protein (His tag)Crystallography grade TREML2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 25-270) protein (His tag)Crystallography grade TREML2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 19-321) protein (rho-1D4 tag)Crystallography grade TREML2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 25-329) protein (rho-1D4 tag)Crystallography grade TREML2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))
- 别名
- TREML2/TLT2 (TREML2 产品)
- 别名
- TREM-B2V1 Protein, C6orf76 Protein, TLT-2 Protein, TLT2 Protein, dJ238O23.1 Protein, AW049306 Protein, Gm750 Protein, Tlt2 Protein, triggering receptor expressed on myeloid cells like 2 Protein, triggering receptor expressed on myeloid cells-like 2 Protein, TREML2 Protein, Treml2 Protein
- 背景
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Background: Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. TREML2 is detected in cultured B cells, T cell leukemia and monocyte leukemia. TREML2 is expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML2 acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. Murine B7-H3 specifically bound to Triggering receptor expressed on myeloid cells (TREM)-like transcript 2 (TLT-2, TREML2). TREML2 was expressed on CD8(+) T cells constitutively and on activated CD4(+) T cells. Stimulation with B7-H3 transfectants preferentially up-regulated the proliferation and IFN-gamma production of CD8(+) T cells. Transduction of TREML2 into T cells resulted in enhanced IL-2 and IFN-gamma production via interactions with B7-H3. There maybe a direct interaction between B7-H3 and TREML2 that preferentially enhances CD8(+) T cell activation.
Synonym: Trem-like transcript 2 protein;TLT2; Triggering receptor expressed on myeloid cells-like protein 2; TLT2;C6orf76
- 分子量
- 28.5 kDa
- NCBI登录号
- NP_079083
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