CD300LB Protein (Fc Tag)
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- 抗原 See all CD300LB (TREM5) 蛋白
- CD300LB (TREM5) (Triggering Receptor Expressed On Myeloid Cells 5 (TREM5))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This CD300LB protein is labelled with Fc Tag.
- 原理
- Recombinant Human CD300LB/LMIR5 (C-Fc)
- 序列
- Ile55-His187
- 产品特性
- Recombinant Human CD300LB is produced by our Mammalian expression system and the target gene encoding Ile55-His187 is expressed with a Fc tag at the C-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TREM5 蛋白
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Triggering Receptor Expressed On Myeloid Cells 5 (TREM5) (AA 1-238) protein (GST tag)
TREM5 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Triggering Receptor Expressed On Myeloid Cells 5 (TREM5) (AA 18-151) protein (His tag)Crystallography grade TREM5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Triggering Receptor Expressed On Myeloid Cells 5 (TREM5) (AA 18-157) protein (His tag)Crystallography grade TREM5 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Triggering Receptor Expressed On Myeloid Cells 5 (TREM5) (AA 18-201) protein (rho-1D4 tag)Crystallography grade TREM5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Triggering Receptor Expressed On Myeloid Cells 5 (TREM5) (AA 18-209) protein (rho-1D4 tag)Crystallography grade TREM5 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Triggering Receptor Expressed On Myeloid Cells 5 (TREM5) (AA 18-151) protein (His tag)TREM5 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CD300LB (TREM5) (Triggering Receptor Expressed On Myeloid Cells 5 (TREM5))
- 别名
- CD300LB/LMIR5 (TREM5 产品)
- 别名
- CLM-7 Protein, Clm7 Protein, Gm253 Protein, LMIR5 Protein, CD300b Protein, CLM7 Protein, CMRF35-A2 Protein, IREM-3 Protein, IREM3 Protein, TREM-5 Protein, TREM5 Protein, CD300 molecule like family member B Protein, CD300 molecule like family member b Protein, triggering receptor expressed on myeloid cells 5 Protein, Cd300lb Protein, CD300LB Protein, Trem5 Protein
- 背景
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Background: CD300LB, also known as CD300b, LMIR5, CLM-7, and IREM-3, is a glycoprotein member of the immunoglobulin superfamily. LMIR5 is expressed on the surface of myeloid lineage cells. It forms noncovalent cis-homodimers and cis-heterodimers with other CD300 family proteins, and the composition of these dimers affects the cellular response. Antibody cross-linking of LMIR5 induces mast cell granule release and cytokine production as well as its tyrosine phosphorylation of LMIR5 (in human). LMIR5 interacts with TIM1 and TIM4 which regulate T cell activation and are themselves binding partners. TIM1 interactions with LMIR5 mediate mast cell activation and the accumulation of neutrophils at sites of TIM1 up-regulation on damaged renal tubule epithelial cells. Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.
Synonym: CD300b, CLM-7, CLM-7, CMRF35-A2, IREM-3, IREM3, TREM-5, TREM5, CD300LB
- 分子量
- 42.2 kDa
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