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- 抗原 See all TREM2 蛋白
- TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- 人细胞
- 标记
- This TREM2 protein is labelled with Fc Tag.
- 原理
- Recombinant Mouse TREM2 Protein (Fc Tag)
- 序列
- Leu19-Pro168
- 产品特性
- Recombinant Mouse Triggering Receptor Expressed on Myeloid Cells 2b is produced by our Mammalian expression system and the target gene encoding Leu19-Pro168 is expressed with a Fc tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TREM2 蛋白
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Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-174) protein (Fc Tag)
TREM2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) protein (His-Avi Tag,Biotin)TREM2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-174) protein (His tag)TREM2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-174) protein (His tag)TREM2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-171) protein (His tag)TREM2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-161) protein (His tag)TREM2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 1-222) protein (GST tag)TREM2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-171) protein (His tag)Crystallography grade TREM2 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-230) protein (rho-1D4 tag)Crystallography grade TREM2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-227) protein (rho-1D4 tag)Crystallography grade TREM2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
- 别名
- TREM2 (TREM2 产品)
- 别名
- TREM-A1 Protein, TREM-B1 Protein, TREM2 Protein, trem-2 Protein, trem2a Protein, trem2b Protein, trem2c Protein, TREM-2 Protein, Trem2a Protein, Trem2b Protein, Trem2c Protein, triggering receptor expressed on myeloid cells 2 Protein, trem-like transcript 2 protein Protein, TREM2 Protein, trem2 Protein, LOC100228399 Protein, Trem2 Protein
- 背景
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Background: Triggering receptor expressed on myeloid cells-2 (TREM-2) is a cell surface receptor primarily expressed on macrophages, osteoclasts, microglia and dendritic cells. TREM-2 is one member of the TREM family, inhibiting the releasing of inflammatory mediators, so it is an important in vivo anti-inflammatory receptor. TREM-2 consists of an 18 aa signal sequence, a 153 aa extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. A soluble form of TREM-2 (TREM-2b) created by alternate splicing diverges at aa 161. TREM-2 transduces intracellular signals through the adaptor DAP12. After binding of TREM-2 with ligand, the TREM-2/DAP12 (dead-cell-activated-receptor-associated protein)-mediated signal transduction pathway causes a series of intracellular protein tyrosine phosphorylation reactions and enzymatic reactions, which then activate the myeloid cells and participate T cell responses.
Synonym: Triggering Receptor Expressed on Myeloid Cells 2b, Triggering receptor expressed on myeloid cells 2, TREM-2, Triggering receptor expressed on monocytes 2, Trem2, Trem2a, Trem2b, Trem2c, TREM-2b
- 分子量
- 43.7 kDa
- UniProt
- Q99NH8
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