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TRIB2 Protein (GST tag,His tag)

TRIB2 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7198335
发货至: 中国
  • 抗原 See all TRIB2 蛋白
    TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 1
    • 1
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    • 1
    • 1
    Baculovirus infected Insect Cells
    标记
    This TRIB2 protein is labelled with GST tag,His tag.
    原理
    Recombinant Human TRIB2/TRB2 Protein (His & GST Tag)
    序列
    Met 1-Asn 343
    产品特性
    A DNA sequence encoding the human TRIB2 (NP_067675.1) (Met 1-Asn 343) was fused with the GST tag at the N-terminus and a polyhistidine tag at the C-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TRIB2 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as sterile 50 mM Tris, 100 mM NaCl, 0.5 mM PMSF, 0.5 mM GSH, pH 8.0
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
    别名
    TRIB2/TRB2 (TRIB2 产品)
    别名
    TRIB2 Protein, Trb2 Protein, Xtrbl Protein, gs3955 Protein, c5fw Protein, trb2 Protein, xtrb2 Protein, TRB2 Protein, C5FW Protein, GS3955 Protein, TRB-2 Protein, AW319517 Protein, RGD1564451 Protein, tribbles pseudokinase 2 Protein, tribbles pseudokinase 2 S homeolog Protein, TRIB2 Protein, trib2 Protein, trib2.S Protein, Trib2 Protein
    背景

    Background: Tribbles homolog 2, also known as TRB-2, and Trib2, is a member of the protein kinase superfamily and Tribbles subfamily (Trib1, Trib2, Trib3). The identification of tribbles as regulators of signal processing systems and physiological processes, including development, together with their potential involvement in diabetes and cancer, has generated considerable interest in these proteins. Tribbles have been reported to regulate activation of a number of intracellular signalling pathways with roles extending from mitosis and cell activation to apoptosis and modulation of gene expression. Tribbles controls the timing of mitosis in the prospective mesoderm, allowing cell-shape changes to be completed. This mechanism for coordinating cell division and cell-shape changes may have helped Drosophila to evolve its mode of rapid early development. Trib2 was identified as a downregulated transcript in leukemic cells undergoing growth arrest. Trib2-transduced bone marrow cells exhibited a growth advantage and readily established factor-dependent cell lines. Trib2-reconstituted mice uniformly developed fatal transplantable acute myelogenous leukemia (AML).

    Synonym: C5FW,FLJ57420,GS3955,TRB2,TRIB2

    分子量
    66 kDa
    NCBI登录号
    NP_067675
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