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TMEM27 Protein (Fc Tag)

TMEM27 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317264
发货至: 中国
  • 抗原 See all TMEM27 蛋白
    TMEM27 (Transmembrane Protein 27 (TMEM27))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 4
    • 2
    • 2
    • 1
    资源
    • 8
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This TMEM27 protein is labelled with Fc Tag.
    原理
    Recombinant Human TMEM27 Protein (Fc Tag)
    序列
    Met 1-Pro141
    产品特性
    A DNA sequence encoding the human TMEM27 (Q9HBJ8) (Met1-Pro141) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TMEM27 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    TMEM27 (Transmembrane Protein 27 (TMEM27))
    别名
    TMEM27 (TMEM27 产品)
    别名
    NX17 Protein, nx-17 Protein, MGC68634 Protein, collectrin Protein, tmem27 Protein, NX-17 Protein, 0610008J07Rik Protein, Nx17 Protein, transmembrane protein 27 L homeolog Protein, si:dkey-194e6.1 Protein, transmembrane protein 27 Protein, tmem27.L Protein, si:dkey-194e6.1 Protein, TMEM27 Protein, tmem27 Protein, Tmem27 Protein
    背景

    Background: TMEM27 is a membrane protein. It has been proposed as a beta cell mass biomarker since it is cleaved and shed by pancreatic beta cells. Overexpression of TMEM27 leads to increased thymidine incorporation, whereas silencing of Tmem27 using RNAi results in a reduction of cell replication. Furthermore, transgenic mice with increased expression of Tmem27 in pancreatic beta cells exhibit increased beta cell mass. TMEM27 is also important for trafficking amino acid transporters to the apical brush border of proximal tubules.

    Synonym: NX-17,NX17

    分子量
    41.4 kDa
    UniProt
    Q9HBJ8
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