TGFB1 蛋白
Quick Overview for TGFB1 蛋白 (ABIN7318102)
抗原
See all TGFB1 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human TGFB1/TGF-beta 1 Protein (Active)
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序列
- Ala279-Ser390
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产品特性
- Recombinant Human Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T cells. The ED50 for this effect is 0.04-0.2 ng/ml
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Transforming Growth Factor, beta 1 (TGFB1) (AA 30-278) protein (His-Avi Tag,Biotin)
TGFB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) proteinTGFB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) protein (AVI tag,Biotin)TGFB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 1 (TGFB1) (AA 30-390) (Active) protein (His tag)TGFB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Transforming Growth Factor, beta 1 (TGFB1) (AA 30-390) (Active) protein (His tag,AVI tag,Biotin)TGFB1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Transforming Growth Factor, beta 1 (TGFB1) (AA 30-278) (Active) protein (His tag,AVI tag,Biotin)TGFB1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Transforming Growth Factor, beta 1 (TGFB1) (Active) proteinTGFB1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active
Transforming Growth Factor, beta 1 (TGFB1) (AA 30-278) protein (His tag)TGFB1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) protein (GST tag)TGFB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Transforming Growth Factor, beta 1 (TGFB1) (AA 281-390) protein (GST tag)TGFB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 50 mM Glycine, 50 mM NaCl, pH 4.0.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
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别名
- TGFB1/TGF-beta 1
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背景
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Background: Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
Synonym: Transforming Growth Factor Beta-1, TGF-Beta-1, Latency-Associated Peptide, LAP, TGFB1, TGFB,CED,DPD1,TGF-beta 1
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分子量
- 12.8 kDa
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UniProt
- P01137
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途径
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
抗原
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