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TK1 Protein (His tag)

TK1 宿主: 人 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319084
发货至: 中国
  • 抗原 See all TK1 蛋白
    TK1 (Thymidine Kinase 1, Soluble (TK1))
    蛋白类型
    Recombinant
    宿主
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    资源
    • 59
    • 5
    • 2
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    • 1
    人细胞
    标记
    This TK1 protein is labelled with His tag.
    原理
    Recombinant Human TK1 Protein (His Tag)
    序列
    Met 1-Asn234
    产品特性
    Recombinant Human Thymidine kinase, Cytosolic is produced by our Mammalian expression system and the target gene encoding Met1-Asn234 is expressed with a 6His tag at the C-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TK1 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM DTT,2 mM EDTA, 10 % Glycerol, pH 7.5.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    TK1 (Thymidine Kinase 1, Soluble (TK1))
    别名
    TK1 (TK1 产品)
    别名
    fi19b06 Protein, zgc:55362 Protein, wu:fi19b06 Protein, TK1 Protein, tk2 Protein, D530002A18Rik Protein, Tk-1 Protein, Tk1a Protein, Tk1b Protein, TK2 Protein, Tk Protein, TK Protein, thymidine kinase 1, soluble Protein, thymidine kinase 1 Protein, thymidine kinase, cytosolic Protein, Thymidine kinase, cytosolic Protein, temporal expression: early Protein, thymidine kinase Protein, Tk thymidine kinase Protein, tk1 Protein, TK1 Protein, EDI_049980 Protein, kith Protein, J2R Protein, HVT031 Protein, Tk1 Protein, tk Protein
    背景

    Background: Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during post-translational modification. Two forms of this protein have been identified in animal cells, one in cytosol TK1 and one in mitochondria TK2. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle, while it is very low in resting cells. TK1 acts as a homotetramer, and can transform thymidime to thymidine 5'-phosphate with the help of ATP

    Synonym: Thymidine kinase, cytosolic,TK1

    分子量
    26.5 kDa
    UniProt
    P04183
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