THSD1 Protein (His tag)
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- 抗原 See all THSD1 蛋白
- THSD1 (Thrombospondin, Type I, Domain Containing 1 (THSD1))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This THSD1 protein is labelled with His tag.
- 原理
- Recombinant Mouse THSD1/TMTSP Protein (His Tag)
- 序列
- Met 1-Asn 412
- 产品特性
- A DNA sequence encoding the extracellular domain of mouse THSD1 (NP_062522.1) (Met 1-Asn 412) was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Thrombospondin, Type I, Domain Containing 1 (THSD1) (Transcript Variant 1) protein (His tag)
THSD1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- THSD1 (Thrombospondin, Type I, Domain Containing 1 (THSD1))
- 别名
- THSD1/TMTSP (THSD1 产品)
- 别名
- 4833423O18Rik Protein, Tmtsp Protein, TMTSP Protein, UNQ3010 Protein, thrombospondin, type I, domain 1 Protein, thrombospondin type 1 domain containing 1 Protein, Thsd1 Protein, THSD1 Protein
- 背景
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Background: Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein which contains one TSP type-1 domain. THSD1 is a multi-domain, multi-functional glycoprotein synthesized by many cells. Matricellular THSD1 modulates cell adhesion and proliferation. It is involved in angiogenesis, inflammation, wound healing and cancer. In vitro, nanomolar concentrations of Thrombospondin-1 are required to alter endothelial and vascular smooth muscle cell adhesion, proliferation, motility, and survival. As a major platelet protein, for a long time it was postulated to control hemostasis via platelet aggregate stabilization. THSD1 is a potent angiogenesis inhibitor, and down-regulation of THSD1 has been suggested to alter tumor growth by modulating angiogenesis in a variety of tumor types.
Synonym: 4833423O18Rik,Tmtsp
- 分子量
- 45 kDa
- NCBI登录号
- NP_062522
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