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TXNL4B Protein (His tag)

TXNL4B 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 92 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317235
发货至: 中国
  • 抗原 See all TXNL4B 蛋白
    TXNL4B (Thioredoxin-Like 4B (TXNL4B))
    蛋白类型
    Recombinant
    宿主
    资源
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This TXNL4B protein is labelled with His tag.
    原理
    Recombinant Human Dim2/TXNL4B Protein (His Tag)
    序列
    Met 1-Ile 149
    产品特性
    A DNA sequence encoding the human TXNL4B (Q9NX01) (Met 1-Ile 149) was expressed, with a polyhistide tag at the N-terminus.
    纯度
    > 92 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product TXNL4B 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, 20 % glycerol, 0.1 % Tween20, 50 mM Arg, pH 7.5
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    TXNL4B (Thioredoxin-Like 4B (TXNL4B))
    别名
    Dim2/TXNL4B (TXNL4B 产品)
    别名
    RGD1305127 Protein, MGC135274 Protein, MGC84953 Protein, DLP Protein, Dim2 Protein, AI595343 Protein, D530025J19Rik Protein, thioredoxin-like 4B Protein, thioredoxin like 4B Protein, thioredoxin like 4B S homeolog Protein, Txnl4b Protein, TXNL4B Protein, txnl4b Protein, txnl4b.S Protein
    背景

    Background: Dim2, also known as TXNL4B, is a member of the DIM1 family. The Dim protein family is composed of two classes, Dim1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in cell cycle progression and have been found to interact with Prp6, an essential component of the spliceosome, which forms the bridge of U4/U6.U5-tri-snRNP. In spite of their biological and structural similarities, Dim1 and Dim2 proteins differ in many aspects. Dim1 bears distinctive structural motifs responsible for its interaction with other spliceosome components. Dim2 forms homodimers and contains specific domains required for its interactions with partners. This originality suggests that although both proteins are involved in pre-mRNA splicing, they are likely to be involved in different biological pathways. Dim2 roduced in E.Coli is a single, non-glycosylated polypeptide chain containing 185 amino acids and having a molecular mass of 21.1kDa. It is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Dim2 has a vital role in pro-mRNA splicing. Dim2 is required in cell cycle progression for S/G2 transition and interacts with PRPF6 subunit of the spliceosome.

    Synonym: Dim2;DLP

    分子量
    19 kDa
    UniProt
    Q9NX01
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