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TXN2 Protein (His tag)

TXN2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7198220
发货至: 中国
  • 抗原 See all TXN2 蛋白
    TXN2 (Thioredoxin 2 (TXN2))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 6
    • 1
    • 1
    • 1
    • 1
    资源
    • 5
    • 3
    • 1
    大肠杆菌(E. Coli)
    标记
    This TXN2 protein is labelled with His tag.
    原理
    Recombinant Human Thioredoxin-2/TXN2 Protein (His Tag)(Active)
    序列
    Thr 60-Gly 166
    产品特性
    A DNA sequence encoding the mature form of human TXN2 (Q99757) (Thr 60-Gly 166) was expressed, with a polyhistide tag at the N-terminus.
    纯度
    > 97 % as determined by reducing SDS-PAGE.
    Biological Activity Comment
    Measured by its ability to catalyze the reduction of insulin. The reaction leads to precipitation, which can be measured by absorbance at 650 nm. The specific activity is 5-8 A650/min/mg.
    Top Product
    Discover our top product TXN2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 8.3
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    TXN2 (Thioredoxin 2 (TXN2))
    别名
    Thioredoxin-2/TXN2 (TXN2 产品)
    别名
    MT-TRX Protein, MTRX Protein, TRX2 Protein, 31884 Protein, CG31884 Protein, CG3864 Protein, DTrx-2 Protein, DmTrx-2 Protein, DmelTrx-2 Protein, Dmel\\CG31884 Protein, Trx Protein, anon-WO0118547.188 Protein, dmtrx-2 Protein, 2510006J11Rik Protein, AI788873 Protein, Trx2 Protein, zgc:77127 Protein, thioredoxin 2 Protein, thioredoxin-2 Protein, thiol reductase thioredoxin Protein, thioredoxin 2 L homeolog Protein, TXN2 Protein, Trx-2 Protein, LOC409451 Protein, VPA0972 Protein, VS_RS18125 Protein, VCD_000568 Protein, VEA_000083 Protein, trx2 Protein, Txn2 Protein, txn2 Protein, txn2.L Protein
    背景

    Background: Thioredoxin-2; also known as TXN2; MTRX and TRX2; is a member of the thioredoxin family. Tryparedoxins (TXN) are thioredoxin-related proteins which; as trypanothione:peroxiredoxin oxidoreductases; constitute the trypanothione-dependent antioxidant defense and may also serve as substrates for ribonucleotide reductase in trypanosomatids. Thioredoxin-2 / TXN2 contains one thioredoxin domain. It is widely expressed in adult (at protein level) and fetal tissues. Human Thioredoxin-2 / TXN2 is a small redox protein important in cellular antioxidant defenses; as well as in the regulation of apoptosis. Thioredoxin-2 / TXN2 has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Thioredoxin-2 / TXN2 could be involved in the resistance to anti-tumor agents. It possesses a dithiol-reducing activity. Thioredoxin-2 / TXN2 plays an important role in protecting the mitochondria against oxidative stress and in sensitizing the cells to ROS-induced apoptosis. Mammalian Thioredoxin-2 / TXN2 is a mitochondrial isoform of highly evolutionary conserved thioredoxins. Thioredoxins are small ubiquitous protein-disulfide oxidoreductases implicated in a large variety of biological functions.

    Synonym: Thioredoxin Mitochondrial; MTRX; Mt-Trx; Thioredoxin-2; TXN2; TRX2

    分子量
    13.4 kDa
    UniProt
    Q99757
    途径
    Cell RedoxHomeostasis
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