TAO Kinase 3 Protein (TAOK3) (AA 1-411) (GST tag,His tag)
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- 抗原 See all TAO Kinase 3 (TAOK3) 蛋白
- TAO Kinase 3 (TAOK3)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 1-411
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This TAO Kinase 3 protein is labelled with GST tag,His tag.
- 原理
- Recombinant Human TAOK3/JIK/MAP3K18 Protein (aa 1-411, His & GST Tag)(Active)
- 序列
- Met 1-Asp 411
- 产品特性
- A DNA sequence encoding the amino acids (Met 1-Asp 411) of human TAOK3 (Q9H2K8-1) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 纯度
- > 92 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- The specific activity was determined to be 10 nmol/min/mg using synthetic PKCtide peptide (ERMRPRKRQGSVRRRV) as substrate.
- Top Product
- Discover our top product TAOK3 蛋白
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile 20 mM Tris, 500 mM NaCl, 3 mM GSH, pH 7.4, 10 % glycerol
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- TAO Kinase 3 (TAOK3)
- 别名
- TAOK3/JIK/MAP3K18 (TAOK3 产品)
- 别名
- TAOK3 Protein, JIK Protein, si:ch1073-179p4.1 Protein, taok3 Protein, DPK Protein, MAP3K18 Protein, 2900006A08Rik Protein, A130052D22 Protein, A430105I05Rik Protein, TAO kinase 3 Protein, TAO kinase 3a Protein, TAOK3 Protein, taok3a Protein, taok3 Protein, Taok3 Protein
- 背景
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Background: Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK / SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, Thousand and one amino acid protein 3, JIK, TAOK3 and MAP3K18, is cytoplasm and peripheral membrane protein which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. Protein kinases are pivotal regulators of cell signaling that modulate each other's functions and activities through site-specific phosphorylation events. TAOK3 / JIK contains one protein kinase domain. TAOK3 / JIK is ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver. TAOK3 / JIK inhibits the basal activity of Jun kinase. It is negatively regulated by epidermal growth factor (EGF). When overexpressed, TAOK3 / JIK may activate ERK1 / ERK2 and JNK / SAPK.
Synonym: DPK;JIK;MAP3K18
- 分子量
- 74.3 kDa
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