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SENP7 Protein (His tag)

SENP7 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319010
发货至: 中国
  • 抗原 See all SENP7 蛋白
    SENP7 (SUMO1/sentrin Specific Protease 7 (SENP7))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 1
    资源
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This SENP7 protein is labelled with His tag.
    原理
    Recombinant Human SENP7 Protein (His Tag)
    序列
    Met695-Ala864
    产品特性
    Recombinant Human Sentrin-Specific Protease 7 is produced by our E.coli expression system and the target gene encoding Met695-Ala864 is expressed with a 6His tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product SENP7 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 5 % Glycerol, pH 7.4.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    SENP7 (SUMO1/sentrin Specific Protease 7 (SENP7))
    别名
    SENP7 (SENP7 产品)
    别名
    SENP7 Protein, 2410152H17Rik Protein, 2810413I22Rik Protein, 2900036C23Rik Protein, 6030449K19Rik Protein, AI790676 Protein, mKIAA1707 Protein, SUMO1/sentrin specific peptidase 7 Protein, SENP7 Protein, Senp7 Protein
    背景

    Background: Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1.

    Synonym: Sentrin-Specific Protease 7, SUMO-1-Specific Protease 2, Sentrin/SUMO-Specific Protease SENP7, SENP7, KIAA1707, SSP2, SUSP2

    分子量
    27.3 kDa
    UniProt
    Q9BQF6
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