SRPK1 Protein (GST tag,His tag)
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- 抗原 See all SRPK1 蛋白
- SRPK1 (SRSF Protein Kinase 1 (SRPK1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This SRPK1 protein is labelled with GST tag,His tag.
- 原理
- Recombinant Human SRPK1 Protein (His & GST Tag)
- 序列
- Glu 2-Ser 655
- 产品特性
- A DNA sequence encoding the human SRPK1 (AAH38292.1) (Glu 2-Ser 655) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 纯度
- > 80 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SRPK1 蛋白
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SRSF Protein Kinase 1 (SRPK1) (AA 1-655) protein (GST tag)
SRPK1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA, KAA
SRSF Protein Kinase 1 (SRPK1) (AA 1-654) (Active) protein (GST tag)SRPK1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func Active
SRSF Protein Kinase 1 (SRPK1) (AA 1-655) (Active) protein (His-GST)SRPK1 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
SRSF Protein Kinase 1 (SRPK1) (AA 371-470) protein (GST tag)SRPK1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
SRSF Protein Kinase 1 (SRPK1) (AA 1-655) protein (Strep Tag)Crystallography grade SRPK1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
SRSF Protein Kinase 1 (SRPK1) (AA 1-648) protein (Strep Tag)Crystallography grade SRPK1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 2 mM GSH, 10 % glycerol, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SRPK1 (SRSF Protein Kinase 1 (SRPK1))
- 别名
- SRPK1 (SRPK1 产品)
- 别名
- SFRSK1 Protein, AU017960 Protein, BEST:CK01209 Protein, CG11489 Protein, CG9085 Protein, CK01209 Protein, Dmel\\CG11489 Protein, SRPK Protein, SRPK1 Protein, Srpk79D Protein, atc Protein, srpk1 Protein, zgc:63789 Protein, wu:fc06h03 Protein, zgc:158800 Protein, sfrsk1 Protein, SRSF protein kinase 1 Protein, serine/arginine-rich protein specific kinase 1 Protein, Serine-arginine protein kinase at 79D Protein, SRSF protein kinase 1a Protein, SRSF protein kinase 1b Protein, SRSF protein kinase 1 S homeolog Protein, SRPK1 Protein, Srpk1 Protein, Srpk79D Protein, srpk1a Protein, srpk1b Protein, srpk1.S Protein
- 背景
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Background: Serine / threonine-protein kinase SRPK1, also known as SFRS protein kinase 1, Serine/arginine-rich protein-specific kinase 1, SR-protein-specific kinase 1 and SRPK1, is a cytoplasm and nucleus protein which belongs to the protein kinase superfamily and CMGC Ser/Thr protein kinase family. Isoform 2 of SRPK1 is predominantly expressed in the testis but is also present at lower levels in heart, ovary, small intestine, liver, kidney, pancreas and skeletal muscle. Isoform 1 of SRPK1 is only seen in the testis, at lower levels than isoform 2. SRPK1 hyperphosphorylates RS domain-containing proteins such as SFRS1, SFRS2 and ZRSR2 on serine residues during metaphase but at lower levels during interphase. SRPK1 plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. SRPK1 locks onto SFRS1 to form a stable complex and processively phosphorylates the RS domain. SRPK1 appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.
Synonym: RP3-422H11.1;SFRSK1
- 分子量
- 102 kDa
- 途径
- Toll-Like Receptors Cascades
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