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SPEG Protein (His tag)

SPEG 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % as determined by reducing SDS-PAGE.
产品编号 ABIN7198099
发货至: 中国
  • 抗原 See all SPEG 蛋白
    SPEG (SPEG Complex Locus (SPEG))
    蛋白类型
    Recombinant
    宿主
    资源
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This SPEG protein is labelled with His tag.
    原理
    Recombinant Human SPEG/APEG-1 Protein (His Tag)
    序列
    Met 1-Glu 113
    产品特性
    A DNA sequence encoding the human SPEG isoform 3 (Q15772-4) (Met 1-Glu 113) was fused with a polyhistidine tag at the C-terminus.
    纯度
    > 85 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product SPEG 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as sterile PBS, pH 7.4
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    SPEG (SPEG Complex Locus (SPEG))
    别名
    SPEG/APEG-1 (SPEG 产品)
    别名
    apeg1 Protein, fc31c10 Protein, im:6912258 Protein, wu:fc31c10 Protein, APEG-1 Protein, APEG1 Protein, BPEG Protein, SPEGalpha Protein, SPEGbeta Protein, AW125581 Protein, Apeg1 Protein, D1Bwg1450e Protein, mKIAA1297 Protein, SPEG complex locus a Protein, SPEG complex locus Protein, spega Protein, SPEG Protein, Speg Protein
    背景

    Background: Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein which belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. SPEG / APEG-1 contains two fibronectin type-III domains, nine Ig-like (immunoglobulin-like) domains, two protein kinase domains. Isoform 1 of SPEG is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 of SPEG is predominantly expressed in the aorta. Isoform 3 of SPEG appears to be expressed only in highly differentiated ASMC in normal vessel walls and down-regulated in dedifferentiated ASMC. Isoform 3 of SPEG may have a role in regulating the growth and differentiation of arterial smooth muscle cells. Isoform 3 of SPEG is quickly down-regulated in response to vascular injury, when ASMC cells change from a quiescent to a proliferative phenotype.

    Synonym: APEG-1;APEG1;BPEG;CNM5;SPEGalpha;SPEGbeta

    分子量
    14 kDa
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