SPARCL1 Protein (His tag)
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- 抗原 See all SPARCL1 蛋白
- SPARCL1 (SPARC-Like 1 (Hevin) (SPARCL1))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This SPARCL1 protein is labelled with His tag.
- 原理
- Recombinant Mouse SPARCL1/SPARC-like 1 Protein (His Tag)
- 序列
- Tyr368-Phe650
- 产品特性
- A DNA sequence encoding the mouse Sparcl1 (NP_034227.3) (Tyr368-Phe650) was expressed with a polyhistidine tag at the N-terminus.
- 纯度
- > 90 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product SPARCL1 蛋白
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SPARC-Like 1 (Hevin) (SPARCL1) (AA 18-664) protein (GST tag)
SPARCL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
SPARC-Like 1 (Hevin) (SPARCL1) (AA 17-664) protein (His tag)Crystallography grade SPARCL1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
SPARC-Like 1 (Hevin) (SPARCL1) (AA 17-650) protein (His tag)Crystallography grade SPARCL1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
SPARC-Like 1 (Hevin) (SPARCL1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)SPARCL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
SPARC-Like 1 (Hevin) (SPARCL1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SPARCL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SPARCL1 (SPARC-Like 1 (Hevin) (SPARCL1))
- 别名
- SPARCL1/SPARC-like 1 (SPARCL1 产品)
- 别名
- LOC445896 Protein, SPARCL1 Protein, sparcl Protein, sparcl1 Protein, DKFZp459I2327 Protein, Ecm2 Protein, Sc1 Protein, hevin Protein, mast9 Protein, PIG33 Protein, SC1 Protein, SPARCL-1 Protein, SPARCL1 Protein, SPARC like 1 Protein, SPARC-like 1 Protein, SPARC-like protein 1 Protein, LOC445896 Protein, SPARCL1 Protein, sparcl1 Protein, Sparcl1 Protein
- 背景
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Background: SPARC-like protein 1 (SPARCL1, also known as SC1, high endothelial venule protein, or hevin) is an extracellular matrix-associated, secreted glycoprotein belonging to the secreted protein acidic and rich in cysteine (SPARC) family of matricellular proteins. It contains three conserved structural domains that are implicated in the regulation of cell adhesion, migration, and proliferation. SPARCL1 is expressed during embryogenesis and tissue remodeling and is especially prominent in brain and vasculature. Its down-regulation in a number of cancers and the possibility of its functional compensation by SPARC has led to recent interest in hevin as a tumor suppressor and regulator of angiogenesis. SPARCL1 has antiadhesive properties, and loss of SPARCL1 expression is associated with increased proliferative activity and cell cycle progression. It is suggested that it may influence multiple cellular processes during distinct stages of brain development and function. In addition, SPARCL1 can influence the function of astroglial cells in the developing and mature central nervous system (CNS).
Synonym: Ecm2,hevin,mast9,Sc1
- 分子量
- 34.8 kDa
- NCBI登录号
- NP_034227
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