SLC3A2 Protein (His tag)
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- 抗原 See all SLC3A2 蛋白
- SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This SLC3A2 protein is labelled with His tag.
- 原理
- Recombinant Rat CD98 Protein (His Tag)
- 序列
- Ala100-Ala527
- 产品特性
- A DNA sequence encoding the rat SLC3A2 (Q794F9) (Ala100-Ala527) was expressed with a polyhistidine tag at the N-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product SLC3A2 蛋白
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Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 206-630) protein (His tag)
SLC3A2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 1-529) protein (GST tag)SLC3A2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 203-312) protein (GST tag)SLC3A2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))
- 别名
- CD98 (SLC3A2 产品)
- 别名
- 4F2 Protein, 4F2HC Protein, 4T2HC Protein, CD98 Protein, CD98HC Protein, MDU1 Protein, NACAE Protein, Mdu1 Protein, MGC53951 Protein, slc3a2 Protein, MGC53965 Protein, SLC3A2 Protein, AI314110 Protein, Cd98 Protein, Ly-10 Protein, Ly-m10 Protein, Ly10 Protein, Mgp-2hc Protein, fc65h12 Protein, wu:fc65h12 Protein, id:ibd1327 Protein, sb:cb519 Protein, wu:fe14a07 Protein, wu:fq18d12 Protein, zgc:55813 Protein, solute carrier family 3 member 2 Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2 L homeolog Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2 S homeolog Protein, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2a Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2b Protein, SLC3A2 Protein, Slc3a2 Protein, slc3a2.L Protein, slc3a2.S Protein, slc3a2a Protein, slc3a2b Protein
- 背景
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Background: 4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein which belongs to the SLC3A transporter family. SLC3A2 / MDU1 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. During gestation, expression in the placenta is significantly stronger at full-term than at the mid-trimester stage. SLC3A2 / MDU1 is expressed in HUVECS and at low levels in resting peripheral blood T-lymphocytes and quiescent fibroblasts. It is expressed in fetal liver and in the astrocytic process of primary astrocytic gliomas. SLC3A2 / MDU1 is also expressed in retinal endothelial cells and in the intestinal epithelial cell line Caco2-BBE. SLC3A2 / MDU1 is required for the function of light chain amino-acid transporters. It involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. SLC3A2 / MDU1 is involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7, SLC3A2 / MDU1 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. SLC3A2 / MDU1 plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. It is required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, SLC3A2 / MDU1 is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta.
Synonym: SLC3A2
- 分子量
- 49.7 kDa
- UniProt
- Q794F9
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