SCN3B Protein (His tag)
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- 抗原 See all SCN3B 蛋白
- SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SCN3B protein is labelled with His tag.
- 原理
- Recombinant Human SCN3B Protein (His Tag)
- 序列
- Met 1-Glu159
- 产品特性
- A DNA sequence encoding the mature form of human SCN3B (Q9NY72) extracellular domain (Met1-Glu159) was expressed with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SCN3B 蛋白
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Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 23-159) protein (His tag)
Crystallography grade SCN3B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, Crys, WB
Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 25-159) protein (His tag)Crystallography grade SCN3B 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, Crys, WB
Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 23-215) protein (rho-1D4 tag)Crystallography grade SCN3B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, Crys, WB
Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 25-215) protein (rho-1D4 tag)Crystallography grade SCN3B 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, Crys, WB
Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 23-159) protein (His tag)SCN3B 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)SCN3B 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))
- 别名
- SCN3B (SCN3B 产品)
- 别名
- 1110001K16Rik Protein, 4833414B02Rik Protein, Scnb3 Protein, HSA243396 Protein, SCNB3 Protein, sodium voltage-gated channel beta subunit 3 Protein, sodium channel, voltage-gated, type III, beta Protein, SCN3B Protein, Scn3b Protein
- 背景
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Background: SCN3B (sodium channel, voltage-gated, type III, beta ,human IgG1-Fc chimera) belongs to the sodium channel auxiliary subunit SCN3B family. It contains 1 Ig-like C2-type (immunoglobulin-like) domain. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN3B gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. Defects in SCN3B are the cause of Brugada syndrome type 7. A tachyarrhythmia characterized by right bundle branch block and ST segment elevation on an electrocardiogram. It can cause the ventricles to beat so fast that the blood is prevented from circulating efficiently in the body. When this situation occurs (called ventricular fibrillation), the individual will faint and may die in a few minutes if the heart is not reset.
Synonym: ATFB16,BRGDA7,HSA243396,SCNB3
- 分子量
- 17.2 kDa
- UniProt
- Q9NY72
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