SLITRK1 Protein (His tag,Fc Tag)
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- 抗原 See all SLITRK1 蛋白
- SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SLITRK1 protein is labelled with His tag,Fc Tag.
- 原理
- Recombinant Human SLITRK1 Protein (His & Fc Tag)
- 序列
- Met 1-Ser 616
- 产品特性
- A DNA sequence encoding the extracellular domain (Met 1-Ser 616) of human SLITRK1 (NP_443142.1) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SLITRK1 蛋白
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SLIT and NTRK-Like Family, Member 1 (SLITRK1) (AA 18-622) protein (His tag)
Crystallography grade SLITRK1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
SLIT and NTRK-Like Family, Member 1 (SLITRK1) (AA 18-622) protein (His tag)Crystallography grade SLITRK1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
SLIT and NTRK-Like Family, Member 1 (SLITRK1) (AA 18-696) protein (rho-1D4 tag)Crystallography grade SLITRK1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
SLIT and NTRK-Like Family, Member 1 (SLITRK1) (AA 18-696) protein (rho-1D4 tag)Crystallography grade SLITRK1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 100 mM Glycine, 10 mM NaCl, 50 mM Tris, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))
- 别名
- SLITRK1 (SLITRK1 产品)
- 别名
- DKFZp459G0529 Protein, LRRC12 Protein, TTM Protein, 3200001I04Rik Protein, SLIT and NTRK like family member 1 Protein, SLIT and NTRK-like family, member 1 Protein, SLITRK1 Protein, slitrk1 Protein, Slitrk1 Protein
- 背景
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Background: SLITRK1 (Slit and Trk-like family member 1) is a integral membrane protein belonging to the SLITRK family consists of at least 6 members (SLITRK1-6). They are named and characterized by the presence of two leucine-rich repeats (LRRs) in the extracellular domain similar to those found in a secreted axonal growth-controlling protein, Slit, as well as a C-terminal domain with homology to Trk neurotrophin tyrosine kinase receptors. Expression of SLITRKs are highly restricted to neural tissues, and are identified as the neuronal components modulating the neurite outgrowth. More specifically, SLITRK1 expression is found in the mature neurons of the cerebrum, thalamus and hippocampus, and induces unipolar neurites in cultured neuronal cells. Human SLITRK1 is a 696 amino acid precursor protein, and one truncating frameshift mutation (448 aa) has been linked to Tourette's syndrome, a genetically influenced developmental neuropsychiatric disorder characterized by chronic vocal and motor tics. In addition, all SLITRK genes are differentially expressed in brain tumors, such as astrocytoma, oligodendroglioma, glioblastoma, and are suggested to be useful molecular indicators of brain tumor properties.
Synonym: FLJ54428,KIAA0918,KIAA1910,LRRC12,RP11-395N17.1,SLITRK1,TTM
- 分子量
- 95 kDa
- NCBI登录号
- NP_443142
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