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SLAMF8 Protein (His tag)

SLAMF8 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE Active
产品编号 ABIN7320214
发货至: 中国
  • 抗原 See all SLAMF8 蛋白
    SLAMF8 (SLAM Family Member 8 (SLAMF8))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 6
    • 4
    小鼠
    资源
    • 3
    • 3
    • 3
    • 1
    HEK-293 Cells
    标记
    This SLAMF8 protein is labelled with His tag.
    原理
    Recombinant Mouse SLAMF8 Protein (His Tag)(Active)
    序列
    Met 1-Asp 231
    产品特性
    A DNA sequence encoding the mouse SLAMF8 (NP_083360.2) extracellular domain (Met 1-Asp 231) was fused with the a polyhistidine tag at the C-terminus.
    纯度
    > 80 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to bind biotinylated mouse SLAMF8 in a functional ELISA.
    Top Product
    Discover our top product SLAMF8 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SLAMF8 (SLAM Family Member 8 (SLAMF8))
    别名
    SLAMF8 (SLAMF8 产品)
    别名
    BLAME Protein, CD353 Protein, SBBI42 Protein, 5830408F06Rik Protein, Blame Protein, SLAM family member 8 Protein, Slamf8 Protein, slamf8 Protein, SLAMF8 Protein
    背景

    Background: The signaling lymphocyte activation molecule (SLAM) family includes homophilic and heterophilic receptors that modulate both adaptive and innate immune responses. These receptors share a common ectodomain organization: a membrane-proximal immunoglobulin constant domain and a membrane-distal immunoglobulin variable domain that is responsible for ligand recognition. SLAM family of receptors is expressed by a wide range of immune cells. Through their cytoplasmic domain, SLAM family receptors associate with SLAM-associated protein (SAP)-related molecules, a group of cytoplasmic adaptors composed almost exclusively of an SRC homology 2 domain. SLAM family receptors, in association with SAP family adaptors, have crucial roles during normal immune reactions in innate and adaptive immune cells. Mouse SLAM family member 8, also known as B-lymphocyte activator macrophage expressed, BCM-like membrane protein, SLAMF8 and BLAME, is a single-pass type I  membrane protein. It contains one Ig-like C2-type (immunoglobulin-like) domain. SLAMF8 / BLAME is expressed in lymph node, spleen, thymus and bone marrow. It may play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.

    Synonym: SLAM family member 8; B-lymphocyte activator macrophage expressed; CD353; Slamf8; Blame;SBBI42

    分子量
    24.8 kDa
    NCBI登录号
    NP_083360
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