SIGLEC5 Protein (His tag)
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- 抗原 See all SIGLEC5 蛋白
- SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
- 蛋白类型
- Recombinant
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宿主
- Cynomolgus
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资源
- 人细胞
- 标记
- This SIGLEC5 protein is labelled with His tag.
- 原理
- Recombinant Cynomolgus SIGLEC5/CD170 Protein (His Tag)
- 序列
- Glu17-Gly435
- 产品特性
- Recombinant Cynomolgus SIGLEC5 is produced by our Mammalian expression system and the target gene encoding Glu17-Gly435 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SIGLEC5 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
- 别名
- SIGLEC5/CD170 (SIGLEC5 产品)
- 别名
- CD170 Protein, CD33L2 Protein, OB-BP2 Protein, OBBP2 Protein, SIGLEC-5 Protein, sialic acid binding Ig like lectin 5 Protein, sialic acid-binding Ig-like lectin 5 Protein, sialic acid binding Ig-like lectin 5 Protein, SIGLEC5 Protein, LOC100597560 Protein, Siglec5 Protein
- 背景
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Background: Sialic acid-binding Ig-like lectin 5 is a protein that in Cynomolgus is encoded by the SIGLEC5 gene, Cynomolgus SIGLEC5 cDNA encodes 551 amino acids (aa) that include a 16 aa signal sequence, a 439aa extracellular domain (ECD) with three Ig-like domains, a transmembrane region and a cytoplasma tail. No Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs. Siglec5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Synonym: Sialic acid-binding Ig-like lectin 5, Siglec-5, CD170,CD33L2,OB-BP2,OBBP,OBBP2,SIGLEC-5,SIGLEC5
- 分子量
- 46.8 kDa
- UniProt
- A0A0B4J1D1
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