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SGK3 Protein (GST tag,His tag)

SGK3 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 80 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317498
发货至: 中国
  • 抗原 See all SGK3 蛋白
    SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))
    蛋白类型
    Recombinant
    宿主
    • 9
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    资源
    • 3
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    Baculovirus infected Insect Cells
    标记
    This SGK3 protein is labelled with GST tag,His tag.
    原理
    Recombinant Human SGK3/SGKL Protein (His & GST Tag)
    序列
    Met 1-Leu 496
    产品特性
    A DNA sequence encoding the human SGK3 (Q96BR1-1) (Met 1-Leu 496) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
    纯度
    > 80 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product SGK3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.5 mM PMSF, 10 % glycerol, 1 mM GSH, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))
    别名
    SGK3/SGKL (SGK3 产品)
    别名
    CISK Protein, SGK2 Protein, SGKL Protein, 2510015P22Rik Protein, A330005P07Rik Protein, Cisk Protein, fy Protein, fz Protein, Sgkl Protein, zgc:162253 Protein, serum/glucocorticoid regulated kinase family member 3 Protein, serum/glucocorticoid regulated kinase 3 Protein, serum/glucocorticoid regulated kinase family, member 3 Protein, serine/threonine-protein kinase Sgk3 Protein, SGK3 Protein, Sgk3 Protein, LOC464217 Protein, sgk3 Protein, LOC100231693 Protein, LOC100343709 Protein, LOC100052030 Protein, LOC100521447 Protein
    背景

    Background: Serine / threonine-protein kinase Sgk3, also known as Serum / glucocorticoid-regulated kinase 3, Serum / glucocorticoid-regulated kinase-like and SGK3, is a cytoplasmic vesicle protein which belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. SGK3 contains one AGC-kinase C-terminal domain, one protein kinase domain and one PX (phox homology) domain. Two specific sites of SGK3, one in the kinase domain (Thr-320) and the other in the C-terminal regulatory region (Ser-486), is needed to be phosphorylated for its full activation. SGK3 is expressed in most tissues with highest levels in pancreas, kidney liver, heart and brain and lower levels in lung, placenta and skeletal muscle. SGK3 is involved in the activation of potassium channels. It mediates cell IL-3-dependent survival signals. SGK3 participates in the regulation of HERG by increasing HERG protein abundance in the plasma membrane and may thus modify the duration of the cardiac action potential. SGK3 is also a very important and characteristic molecule that plays a critical role in both hair follicle morphogenesis and hair cycling.

    Synonym: CISK;SGK2;SGKL

    分子量
    85 kDa
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