电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

SERPINB1 Protein (His tag)

SERPINB1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318726
发货至: 中国
  • 抗原 See all SERPINB1 蛋白
    SERPINB1 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1))
    蛋白类型
    Recombinant
    宿主
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    人细胞
    标记
    This SERPINB1 protein is labelled with His tag.
    原理
    Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag)
    序列
    Met 1-Pro379
    产品特性
    Recombinant Human Serine Protease Inhibitor-clade B1 is produced by our Mammalian expression system and the target gene encoding Met1-Pro379 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product SERPINB1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SERPINB1 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1))
    别名
    SERPINB1/PI2 (SERPINB1 产品)
    别名
    ELANH2 Protein, zgc:91981 Protein, si:dkey-177p2.11 Protein, si:dkey-177p2.12 Protein, EI Protein, LEI Protein, M/NEI Protein, MNEI Protein, PI-2 Protein, PI2 Protein, elanh2 Protein, lei Protein, m/nei Protein, mnei Protein, pi2 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 1 Protein, serpin family B member 1 Protein, serpin family B member 1 L homeolog Protein, SERPINB1 Protein, serpinb1 Protein, serpinb1.L Protein
    背景

    Background: SERPINB1 is a member of the serpin family and Ov-serpin subfamily. As protease inhibitors, serpins have an array of functions including regulating blood coagulation, fibrinolysis, the complement pathway, angiogenesis, inflammation, tumor suppression, extracellular matrix remodeling, and cell motility. SERPINB1 regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Reactive bond 1 of SerpinB1 is specific for reaction with chymotrypsin-like protease such as cathepsin G, chymotrypsin or chymase. Reactive bond 2 of SerpinB1 is specific for reaction with elastase-like protease such as neutrophyl elastase, proteinase-3, pancreatic elastase or PSA. In addition, SERPINB1 also functions as a potent intracellular inhibitor of granzyme H.

    Synonym: Leukocyte elastase inhibitor,SERPINB1, Monocyte/neutrophil elastase inhibitor, M/NEI, Peptidase inhibitor 2, PI-2, PI2, EI,ELANH2,HEL-S-27,HEL57,LEI,MNEI,

    分子量
    43.8 kDa
    UniProt
    P30740
You are here: