STK16 Protein (NusA Tag,His tag)
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- 抗原 See all STK16 products
- STK16 (serine/threonine Kinase 16 (STK16))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This STK16 protein is labelled with NusA Tag,His tag.
- 原理
- Recombinant Human STK16/PKL12/MPSK Protein (His & NusA Tag)
- 序列
- Met 1-Ile 305
- 产品特性
- A DNA sequence encoding the native human STK16 (AAH02618.1) (Met 1-Ile 305) was fused with the polyhistidine-tagged NusA tag at the N-terminus.
- 纯度
- > 85 % as determined by reducing SDS-PAGE.
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serine/threonine Kinase 16 (STK16) (AA 1-305) protein (His tag)
STK16 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
serine/threonine Kinase 16 (STK16) (AA 1-305) protein (GST tag)STK16 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
serine/threonine Kinase 16 (STK16) (AA 1-100) protein (GST tag)STK16 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
serine/threonine Kinase 16 (STK16) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)STK16 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
serine/threonine Kinase 16 (STK16) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)STK16 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile PBS, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- STK16 (serine/threonine Kinase 16 (STK16))
- 别名
- STK16/PKL12/MPSK (STK16 产品)
- 别名
- stk16 Protein, STK16 Protein, Stk16 Protein, ACYPI000353 Protein, KRCT Protein, MPSK Protein, PKL12 Protein, TSF1 Protein, EDPK Protein, Krct Protein, TSF-1 Protein, F52 Protein, serine/threonine kinase 16 Protein, serine/threonine kinase 16 L homeolog Protein, serine/threonine-protein kinase Protein, STK16 Protein, stk16.L Protein, stk16 Protein, Stk16 Protein
- 背景
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Background: Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein which is ubiquitously expressed at very low levels. STK16 / MPSK1 belongs to the protein kinase superfamily and Ser/Thr protein kinase family. It contains one protein kinase domain. Transforming growth factor-beta (TGF-beta) shows a variety of biological activities in various organs or cells. Some factors such as Smads (Sma and Mad proteins) and TGF-beta activating kinase 1 have been characterized as signalling molecules downstream of TGF-beta. Several TGF-beta response elements have been identified such as cAMP response element, Smad binding element, and recognition sites for activating protein-1 and stimulating protein-1 in various gene promoters. STK16 / MPSK1 is an unique factor with two biological functions, transcriptional regulation and protein phosphorylation, that may be involved in TGF-beta signals. STK16 / MPSK1 is a protein kinase that act on both serine and threonine residues. STK16 / MPSK1 possessed DNA-binding ability and activated the TGF-beta responsive CNP promoter or vascular endothelial growth factor gene promoter which possesses a sequence element analogous to the TGF-beta responsive GC-rich element of the CNP promoter. STK16 / MPSK1 did not directly activate a Smads-dependent promoter from plasminogen activator inhibitor 1 gene, but it showed enhancement in co-operation with Smad3 and Smad4. STK16 / MPSK1 mRNA as well as its protein level were stimulated by TGF-beta treatment.
Synonym: KRCT;MPSK;PKL12;TSF1
- 分子量
- 92 kDa
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