SHMT1 Protein (His tag)
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- 抗原 See all SHMT1 蛋白
- SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This SHMT1 protein is labelled with His tag.
- 原理
- Recombinant Human SHMT1 Protein (His Tag)
- 序列
- Met3-Phe483
- 产品特性
- Recombinant Human Serine Hydroxymethyltransferase Cytosolic is produced by our Mammalian expression system and the target gene encoding Met3-Phe483 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SHMT1 蛋白
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serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) (AA 1-483) protein (GST tag)
SHMT1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) (AA 374-482) protein (GST tag)SHMT1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) (AA 1-483) protein (His tag)SHMT1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SHMT1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)SHMT1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))
- 别名
- SHMT1 (SHMT1 产品)
- 别名
- Shmt Protein, mShmt Protein, LRRGT00032 Protein, shmt1 Protein, MGC53442 Protein, zgc:66171 Protein, zgc:77524 Protein, SHMT1 Protein, Shmt1 Protein, CSHMT Protein, SHMT Protein, AI324848 Protein, AI385541 Protein, C81125 Protein, mshmt Protein, mshmt1 Protein, mshmt2 Protein, MEL-32 Protein, SHMT2 Protein, F20D10.50 Protein, F20D10_50 Protein, SERINE HYDROXYMETHYLTRANSFERASE 1 Protein, SERINE TRANSHYDROXYMETHYLASE Protein, SERINE TRANSHYDROXYMETHYLTRANSFERASE Protein, STM Protein, serine transhydroxymethyltransferase 1 Protein, serine hydroxymethyltransferase 1 Protein, serine hydroxymethyltransferase 1 (soluble) L homeolog Protein, serine hydroxymethyltransferase 1 (soluble) Protein, microRNA 6778 Protein, serine transhydroxymethyltransferase 1 Protein, Shmt1 Protein, shmt1.L Protein, shmt1 Protein, MIR6778 Protein, SHMT1 Protein, SHM1 Protein
- 背景
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Background: Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon unit for the synthesis of methionine, thymidylate, and purines in the cytoplasm. A reduction in SHMT1 levels would result in less glycine that could affect the nervous system by acting as an agonist to the NMDA receptor and this could be a mechanism behind Smith-Magenis syndrome.
Synonym: Serine Hydroxymethyltransferase Cytosolic, SHMT, Glycine Hydroxymethyltransferase, Serine Methylase, SHMT1
- 分子量
- 53.9 kDa
- UniProt
- P34896
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