SERPINA3N Protein (His tag)
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- 抗原 See all SERPINA3N 蛋白
- SERPINA3N (Serine (Or Cysteine) Peptidase Inhibitor, Clade A, Member 3N (SERPINA3N))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- 人细胞
- 标记
- This SERPINA3N protein is labelled with His tag.
- 原理
- Recombinant Mouse Serpin A3N Protein (His Tag)
- 序列
- Phe21-Lys418
- 产品特性
- Recombinant Mouse Serpin A3N is produced by our Mammalian expression system and the target gene encoding Phe21-Lys418 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Serine (Or Cysteine) Peptidase Inhibitor, Clade A, Member 3N (SERPINA3N) (AA 21-418) protein (His tag)
Crystallography grade SERPINA3N 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0 .
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- SERPINA3N (Serine (Or Cysteine) Peptidase Inhibitor, Clade A, Member 3N (SERPINA3N))
- 别名
- Serpin A3N (SERPINA3N 产品)
- 别名
- Spi2-2 Protein, Spi2.2 Protein, Spi2/eb.4 Protein, CPi-26 Protein, SPI3 Protein, Spi-2.2 Protein, Spin2c Protein, Spin3 Protein, serine (or cysteine) peptidase inhibitor, clade A, member 3N Protein, Serpina3n Protein
- 背景
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Background: Serine protease inhibitor A3N(Serpin A3N) is a serine protease inhibitor that is structurally related to α1 antichymotrypsin encoded by the SERPINA3 gene. Serpin A3N is highly expressed in brain, testis, lung, thymus, and spleen. It is expressed with low levels in bone marrow, kidney and skeletal muscle. Serpin A3N secreted by Sertoli cells may regulate the activity of locally produced Granzyme B. Granzyme B inhibition by Serpin A3N may therefore regulate Granzyme Bmediated killing by cytotoxic lymphocytes, providing a means to disable cellmediated immune responses.
Synonym: Serine protease inhibitor A3N, Serpin A3N, Serpina3n, Spi2
- 分子量
- 45.6 kDa
- UniProt
- Q91WP6
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