SELPLG Protein (His tag,Fc Tag)
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- 抗原 See all SELPLG 蛋白
- SELPLG (Selectin P Ligand (SELPLG))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SELPLG protein is labelled with His tag,Fc Tag.
- 原理
- Recombinant Human PSGL-1/CD162 Protein (His & Fc Tag)
- 序列
- Met 1-Val295
- 产品特性
- A DNA sequence encoding the extracellular domain (Met1-Val295) of human PSGL-1 precursor (AAC50061.1) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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- Discover our top product SELPLG 蛋白
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Selectin P Ligand (SELPLG) (AA 42-307) protein (His tag)
SELPLG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin P Ligand (SELPLG) (AA 34-356) protein (His tag)SELPLG 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin P Ligand (SELPLG) (AA 42-320) protein (His tag)SELPLG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Selectin P Ligand (SELPLG) (AA 18-320) protein (His tag)SELPLG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Selectin P Ligand (SELPLG) protein (Fc Tag)SELPLG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SELPLG (Selectin P Ligand (SELPLG))
- 别名
- PSGL-1/CD162 (SELPLG 产品)
- 别名
- CD162 Protein, CLA Protein, PSGL-1 Protein, PSGL1 Protein, SELPLG Protein, SELPG Protein, Psgl-1 Protein, Psgl1 Protein, Selp1 Protein, Selpl Protein, selectin P ligand Protein, selectin, platelet (p-selectin) ligand Protein, clasper Protein, SELPLG Protein, Selplg Protein, cla Protein
- 背景
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Background: P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~120 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
Synonym: P-selectin glycoprotein ligand 1, PSGL-1, Selectin P ligand, CD162, SELPLG,CLA,PSGL1
- 分子量
- 57.1 kDa
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