SLPI Protein (AA 26-132) (His tag)
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- 抗原 See all SLPI 蛋白
- SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 26-132
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This SLPI protein is labelled with His tag.
- 原理
- Recombinant Human SLPI Protein (aa 26-132, His Tag)(Active)
- 序列
- Ser 26-Ala 132
- 产品特性
- A DNA sequence encoding the secreted form of human SLPI (P03973) (Ser 26-Ala 132) was expressed, with a polyhistidine tag at the N-terminus.
- 纯度
- > 84 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK (Dnp)-NH2 (Catalog # ES002).The IC50 value is <4 Nm.
- Top Product
- Discover our top product SLPI 蛋白
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Secretory Leukocyte Peptidase Inhibitor (SLPI) (AA 26-132) protein (Fc Tag)
SLPI 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Secretory Leukocyte Peptidase Inhibitor (SLPI) (AA 26-131) protein (Fc Tag)SLPI 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Secretory Leukocyte Peptidase Inhibitor (SLPI) (AA 33-132) protein (GST tag)SLPI 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Secretory Leukocyte Peptidase Inhibitor (SLPI) (AA 26-132) protein (GST tag)SLPI 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Secretory Leukocyte Peptidase Inhibitor (SLPI) (AA 26-132) protein (His tag)Crystallography grade SLPI 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Secretory Leukocyte Peptidase Inhibitor (SLPI) (AA 26-131) protein (His tag)Crystallography grade SLPI 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Secretory Leukocyte Peptidase Inhibitor (SLPI) (AA 26-132), (full length) protein (GST tag)SLPI 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))
- 别名
- SLPI (SLPI 产品)
- 别名
- ALK1 Protein, ALP Protein, BLPI Protein, HUSI Protein, HUSI-I Protein, MPI Protein, WAP4 Protein, WFDC4 Protein, MATN4 Protein, SLPI Protein, ckpi Protein, secretory leukocyte peptidase inhibitor Protein, antileukoproteinase Protein, SLPI Protein, Slpi Protein, LOC102174044 Protein
- 背景
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Background: Secretory leukoprotease inhibitor (SLPI), also called antileukoprotease (ALP), is a 12- kDa, nonglycosylated serine protease inhibitor present in mucous secretions. It is thought to play a role in protecting the mucosae from injury associated with inflammation. SLPI is locally produced by serous cells, including bronchial submucosal glands. Elafin and SLPI are members of larger families of proteins secreted predominantly at mucosal sites, and have been shown to be modulated in multiple pathological conditions. Elafin and SLPI are structurally related in that both have a fold with a four-disulfide core or whey acidic protein (WAP) domain responsible for inhibiting proteases. SLPI is a prominent innate immune protein of the respiratory tract, possessing serine protease inhibitor activity, antibacterial activity, and anti-inflammatory/immunomodulatory activity.
Synonym: ALK1,ALP,BLPI,HUSI,HUSI-I,MPI,WAP4,WFDC4
- 分子量
- 14 kDa
- UniProt
- P03973
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