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SCGN Protein (His tag)

SCGN 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317381
发货至: 中国
  • 抗原 See all SCGN 蛋白
    SCGN (Secretagogin, EF-Hand Calcium Binding Protein (SCGN))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    资源
    • 4
    • 3
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This SCGN protein is labelled with His tag.
    原理
    Recombinant Human SCGN/Secretagogin Protein (E.coli, His Tag)
    序列
    Asp 2-Pro 276
    产品特性
    A DNA sequence encoding the human SCGN (NP_008929.2) (Asp 2-Pro 276) was expressed, with a polyhistide tag at the N-terminus.
    纯度
    > 97 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product SCGN 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SCGN (Secretagogin, EF-Hand Calcium Binding Protein (SCGN))
    别名
    SCGN/Secreogin (SCGN 产品)
    别名
    SCGN Protein, MGC146683 Protein, CALBL Protein, DJ501N12.8 Protein, SECRET Protein, SEGN Protein, setagin Protein, zgc:100843 Protein, secretagogin, EF-hand calcium binding protein Protein, Secretagogin Protein, secretagogin, EF-hand calcium binding protein L homeolog Protein, SCGN Protein, scgn Protein, segn Protein, scgn.L Protein, Scgn Protein
    背景

    Background: Secretagogin, also known as SCGN, is a secreted protein which is detectable in human serum after ischemic neuronal damage. It is a recently described calcium-binding protein. Secretagogin / SCGN is expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression of Secretagogin / SCGN is restricted to distinct subtypes of neurons with highest expression in the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland, in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons. Secretagogin / SCGN is widely expressed in prostatic adenocarcinoma as opposed to adenocarcinomas in other organs. The function of Secretagogin / SCGN is unknown, but it has been suggested in beta-cells to influence calcium-influx and has been observed downregulated in diabetes-prone BB rat islets exposed to cytokines. Secretagogin / SCGN is involved in the calcium metabolism of tumour cells and endothelial cells in a subset of neoplasms of the brain and its coverings. Secretagogin / SCGN is also a novel marker for neuroendocrine differentiation.

    Synonym: Secretagogin, SCGN, SECRET,CALBL,DJ501N12.8,setagin

    分子量
    33.4 kDa
    NCBI登录号
    NP_008929
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