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S100A7 蛋白

S100A7 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319482
发货至: 中国
  • 抗原 See all S100A7 蛋白
    S100A7 (S100 Calcium Binding Protein A7 (S100A7))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 4
    • 2
    • 1
    资源
    • 9
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Human S100A7/PSOR1 Protein
    序列
    Met1-Gln101
    产品特性
    Recombinant Human S100A7 is produced by our E.coli expression system and the target gene encoding Met1-Gln101 is expressed.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product S100A7 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    S100A7 (S100 Calcium Binding Protein A7 (S100A7))
    别名
    S100A7/PSOR1 (S100A7 产品)
    别名
    PSOR1 Protein, S100A7c Protein, S100A7 Protein, S100 calcium binding protein A7 Protein, protein S100-A7 Protein, S100A7 Protein, LOC469501 Protein, LOC713189 Protein, LOC714943 Protein, LOC101104285 Protein, LOC102191570 Protein
    背景

    Background: S100A7 is a 11-12 kDa member of the S100 family of EF hand calcium binding proteins. Human S100A7 shares 32 % amino acid sequence identity with mouse S100A7A, the closest related protein in mouse. It is acetylated at the N-terminus and binds both calcium and zinc ions. S100A7 is up-regulated in keratinocytes of psoriasis and atopic dermatitis lesions, as well as in epithelial cells of the tongue, eye, and female genital tract. Its up-regulation can be induced by bacterial exposure, inflammatory cytokines, or epidermal barrier disruption. S100A7 supports epithelial integrity through killing E. coli by sequestration of zinc and through inducing the up-regulation of tight junction proteins. The interaction of S100A7 with RAGE promotes the migration of immune cells and the infiltration of macrophages into tumor sites.

    Synonym: Protein S100-A7, Psoriasin, S100 calcium-binding protein A7, S100A7, PSOR1, S100A7C

    分子量
    11.5 kDa
    UniProt
    P31151
    途径
    S100 Proteins
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