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S100A2 Protein (Fc Tag)

S100A2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317982
发货至: 中国
  • 抗原 See all S100A2 蛋白
    S100A2 (S100 Calcium Binding Protein A2 (S100A2))
    蛋白类型
    Recombinant
    宿主
    • 9
    • 2
    资源
    • 7
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This S100A2 protein is labelled with Fc Tag.
    原理
    Recombinant Human S100A2 Protein (Fc Tag)
    序列
    Met 2-Pro98
    产品特性
    A DNA sequence encoding the human S100A2 (NP_005969.1) (Met 2-Pro98) was expressed with the fused Fc region of human IgG1 at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product S100A2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 100 mM Glycine, 10 mM NaCl, 50 mM Tris, pH 7.5
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    S100A2 (S100 Calcium Binding Protein A2 (S100A2))
    别名
    S100A2 (S100A2 产品)
    别名
    S100A2 Protein, CAN19 Protein, S100L Protein, CaN19 Protein, EG628324 Protein, S100 calcium binding protein A2 Protein, S100A2 Protein, S100a2 Protein
    背景

    Background: The calcium-binding Protein S100A2 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 family genes are located as a cluster on chromosome 1q21, and S100 proteins consisting of at least 20 members are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. S100A2 was first detected in lung and kidney, and is mainly expressed in a subset of tissues and cells such as breast epithelia and liver. The S100A2 protein is a homodimer that undergoes a conformational change upon binding of calcium, and the active form functions in regulating cell proliferation and differentiation, gene transcription, and p53-dependent growth arrest and apoptosis. Accordingly, this protein is regarded as a putative tumor suppressor, and thus chromosomal rearrangements and reduced expression of S100A2 gene have been implicated in certain carcinomas.

    Synonym: Protein S100-A2, CAN19, Protein S-100L, S100 calcium-binding protein A2, S100A2, S100L

    分子量
    37.6 kDa
    NCBI登录号
    NP_005969
    途径
    S100 Proteins
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