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S100A10 Protein (His tag)

S100A10 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317644
发货至: 中国
  • 抗原 See all S100A10 蛋白
    S100A10 (S100 Calcium Binding Protein A10 (S100A10))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    资源
    • 14
    • 5
    • 1
    大肠杆菌(E. Coli)
    标记
    This S100A10 protein is labelled with His tag.
    原理
    Recombinant Human S100A10 Protein (His Tag)
    序列
    Pro 2-Lys 97
    产品特性
    A DNA sequence encoding the human S100A10 (NP_002957.1) (Pro 2-Lys 97) was expressed, with a polyhistidine tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product S100A10 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 20 mM Tris, pH 8.5, 10 % glycerol
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    S100A10 (S100 Calcium Binding Protein A10 (S100A10))
    别名
    S100A10 (S100A10 产品)
    别名
    42C Protein, ANX2L Protein, ANX2LG Protein, CAL1L Protein, CLP11 Protein, Ca[1] Protein, GP11 Protein, P11 Protein, p10 Protein, AA409961 Protein, AL024248 Protein, CAL12 Protein, Cal1l Protein, p11 Protein, s100a10 Protein, 42c Protein, anx2l Protein, anx2lg Protein, cal1l Protein, calpactin Protein, clp11 Protein, gp11 Protein, p11-A Protein, s100a10b Protein, hm:zehn1116 Protein, wu:fa94d11 Protein, wu:fb05h04 Protein, zgc:56142 Protein, zgc:101880 Protein, S100 calcium binding protein A10 Protein, S100 calcium binding protein A10 (calpactin) Protein, S100 calcium binding protein A10 L homeolog Protein, S100 calcium binding protein A10b Protein, S100 calcium binding protein A10a Protein, S100A10 Protein, S100a10 Protein, s100a10 Protein, s100a10.L Protein, s100a10b Protein, s100a10a Protein
    背景

    Background: S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response.   Protein S100-A10, also known as Calpactin I light chain, Cellular ligand of annexin II, S100 calcium-binding protein A10, p10 protein, p11, ANX2LG and S100A10, is a member of the S100 family of small, dimeric EF hand-type Ca(2+)-binding proteins that generally modulate cellular target proteins in response to intracellular Ca(2+) signals. In contrast to all other S100 proteins, S100A10 is Ca(2+) insensitive because of amino acid replacements in its Ca(2+)-binding loops that lock the protein in a permanently active state. S100A10 forms a heterotetramer with annexin IIH and promotes carcinoma invasion and metastasis by plasminogen activation. S100A10 and annexin II contribute to the aggressive characteristics of anaplastic carcinoma, while playing a constitutive role in papillary carcinoma. S100A10 induces the dimerization of ANXA2 / p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target of tyrosine-specific kinase. S100A10 functions as a linker tethering certain transmembrane proteins to annexin A2 thereby assisting their traffic to the plasma membrane and/or their firm anchorage at certain membrane sites.

    Synonym: 42C;ANX2L;ANX2LG;CAL1L;Ca[1];CLP11;GP11;MGC111133;p10;P11

    分子量
    12.6 kDa
    NCBI登录号
    NP_002957
    途径
    S100 Proteins
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