RBP4 Protein (His tag)
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- 抗原 See all RBP4 蛋白
- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This RBP4 protein is labelled with His tag.
- 原理
- Recombinant Mouse RBP4 Protein (His Tag)(Active)
- 序列
- Met 1-Leu 201
- 产品特性
- A DNA sequence encoding the mouse RBP4 (NP_035385.1) (Met 1-Leu 201) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to bind alltrans retinoic acid. The binding of retinoic acid results in the quenching of Trp fluorescence in RBP4.The 50% binding concentration (BC50) is >0.5 M
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- Discover our top product RBP4 蛋白
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Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) protein (His tag)
RBP4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) protein (GST tag)RBP4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Retinol Binding Protein 4, Plasma (RBP4) (AA 103-201) protein (GST tag)RBP4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) protein (His tag)RBP4 宿主: 人 宿主: HEK-293T Cells Recombinant SDS
Retinol Binding Protein 4, Plasma (RBP4) (Active) protein (His tag)RBP4 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Retinol Binding Protein 4, Plasma (RBP4) (AA 19-194) protein (His tag)Crystallography grade RBP4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Retinol Binding Protein 4, Plasma (RBP4) (AA 19-197) protein (His tag)Crystallography grade RBP4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Retinol Binding Protein 4, Plasma (RBP4) (AA 19-199) protein (His tag)Crystallography grade RBP4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Retinol Binding Protein 4, Plasma (RBP4) (AA 19-200) protein (His tag)Crystallography grade RBP4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
- 别名
- RBP4 (RBP4 产品)
- 别名
- RDCCAS Protein, RBP Protein, RNBP Protein, rbp4 Protein, MGC54038 Protein, srbp Protein, PRBP Protein, RBPA Protein, Rbp-4 Protein, fb23c12 Protein, rbp Protein, wu:fb23c12 Protein, wu:fb58d04 Protein, wu:fb72b04 Protein, zgc:86911 Protein, retinol binding protein 4 Protein, renin binding protein Protein, retinol binding protein 4 S homeolog Protein, retinol binding protein 4 A, plasma Protein, retinol binding protein 4, plasma Protein, retinol binding protein 4 L homeolog Protein, RBP4 Protein, RENBP Protein, rbp4.S Protein, rbp4 Protein, Rbp4 Protein, RBP4A Protein, rbp4.L Protein
- 背景
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Background: Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex in plasma through their tight interaction. As a member of the lipocalin superfamily, RBP4 containing a β-barrel structure with a well-defined cavity is secreted from the liver, and in turn delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), and this binding is crucial for preventing RBP4 excretion through the kidney glomeruli. RBP4 expressed from an ectopic source efficiently delivers retinol to the eyes, and its deficiency affects night vision largely. Recently, RBP4 as an adipokine, is found to be expressed in adipose tissue and correlated with obesity, insulin resistance (IR) and type 2 diabetes (T2DM).
Synonym: Rbp-4
- 分子量
- 22.8 kDa
- NCBI登录号
- NP_035385
- 途径
- Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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