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Chemerin Protein (His tag)

RARRES2 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318984
发货至: 中国
  • 抗原 See all Chemerin (RARRES2) 蛋白
    Chemerin (RARRES2) (Retinoic Acid Receptor Responder (Tazarotene Induced) 2 (RARRES2))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 4
    • 2
    • 1
    • 1
    资源
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    人细胞
    标记
    This Chemerin protein is labelled with His tag.
    原理
    Recombinant Human RARRES2/TIG2 Protein (His Tag)
    序列
    Glu21-Ser157
    产品特性
    Recombinant Human Retinoic acid receptor responder protein 2 is produced by our Mammalian expression system and the target gene encoding Glu21-Ser157 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product RARRES2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Chemerin (RARRES2) (Retinoic Acid Receptor Responder (Tazarotene Induced) 2 (RARRES2))
    别名
    RARRES2/TIG2 (RARRES2 产品)
    别名
    HP10433 Protein, TIG2 Protein, 0610007L05Rik Protein, AI303516 Protein, retinoic acid receptor responder 2 Protein, retinoic acid receptor responder (tazarotene induced) 2 Protein, RARRES2 Protein, Rarres2 Protein
    背景

    Background: Retinoic acid receptor responder protein 2(RARRES2) is a secreted protein that in humans is encoded by the RARRES2 gene. It is highly expressed in skin, also found in pancreas, liver, spleen, prostate, ovary, small intestine and colon. It is a chemoattractant protein that acts as a ligand for the G protein-coupled receptor CMKLR1. RARRES2 is secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. It is thought to act as a cell surface receptor, found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation. RARRES2 is inhibited in psoriatic lesions,it is activated by tazarotene in skin rafts and in the epidermis of psoriatic lesions.

    Synonym: Retinoic acid receptor responder protein 2, Chemerin, RAR-responsive protein TIG2, Tazarotene-induced gene 2 protein, RARRES2, TIG2

    分子量
    16.9 kDa
    UniProt
    Q99969
    途径
    Brown Fat Cell Differentiation
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