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RCN3 Protein (AA 1-324) (His tag)

RCN3 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317231
发货至: 中国
  • 抗原 See all RCN3 蛋白
    RCN3 (Reticulocalbin 3, EF-Hand Calcium Binding Domain (RCN3))
    蛋白类型
    Recombinant
    产品特性
    AA 1-324
    宿主
    • 3
    • 2
    • 1
    资源
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This RCN3 protein is labelled with His tag.
    原理
    Recombinant Human Reticulocalbin 3/RCN3 Protein (aa 1-324, His Tag)
    序列
    Met 1-His324
    产品特性
    A DNA sequence encoding the human RCN3 (Q96D15) (Met1-His324) was expressed with a polyhistidine tag at the C-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product RCN3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    RCN3 (Reticulocalbin 3, EF-Hand Calcium Binding Domain (RCN3))
    别名
    Reticulocalbin 3/RCN3 (RCN3 产品)
    别名
    RLP49 Protein, 6030455P07Rik Protein, D530026G20Rik Protein, D7Ertd671e Protein, reticulocalbin 3 Protein, reticulocalbin 3, EF-hand calcium binding domain Protein, RCN3 Protein, Rcn3 Protein
    背景

    Background: RCN3 belongs to the CREC family which contains multiple EF-hand Ca2+-binding proteins localized to the secretory pathway. RCN3 sequence is characterized by the presence of five Arg-Xaa-Xaa-Arg motifs, which represents the target sequence of subtilisin-like proprotein convertases(SPCs). SPCs are a family of seven structurally related serine endoproteases that are involved in the proteolytic activation of proproteins.RCN3 is transiently associated with proPACE4, but not with mature PACE4. Inhibition of PACE4 maturation by a Ca2+ ionophore resulted in accumulation of the proPACE4-RCN-3 complex in cells. It has been proposed that elective and transient association of RCN3 with the precursor of PACE4 plays an important role in the biosynthesis of PACE4.

    Synonym: Reticulocalbin-3, EF-Hand Calcium-Binding Protein RLP49, RCN3

    分子量
    36.2 kDa
    UniProt
    Q96D15
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