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RELT Protein (His tag,Fc Tag)

RELT 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317836
发货至: 中国
  • 抗原 See all RELT 蛋白
    RELT (RELT Tumor Necrosis Factor Receptor (RELT))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 3
    • 1
    资源
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This RELT protein is labelled with His tag,Fc Tag.
    原理
    Recombinant Human RELT/TNFRSF19L Protein (His & Fc Tag)
    序列
    Met 1-Ala 160
    产品特性
    A DNA sequence encoding the human RELT (NP_116260.2) extracellular domain (Met 1-Ala 160) with 127R/G & 129R/G mutation was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product RELT 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    RELT (RELT Tumor Necrosis Factor Receptor (RELT))
    别名
    RELT/TNFRSF19L (RELT 产品)
    别名
    E430021K24Rik Protein, Tnfrsf19l Protein, zgc:77246 Protein, TNFRSF19L Protein, TRLT Protein, RELT tumor necrosis factor receptor Protein, RELT, TNF receptor Protein, Relt Protein, relt Protein, RELT Protein
    背景

    Background: Receptor expressed in lymphoid tissues (RELT); also known as tumor necrosis factor receptor superfamily; member 19-like (TNFRSF19L); is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1. RELT/TNFRSF19L is capable of stimulating T-cell proliferation in the presence of CD3 signaling; which suggests its regulatory role in immune response. RELT/TNFRSF19L is a type I transmembrane glycoprotein with a cysteine-rich extracellular domain; possessing significant homology to other members of the TNFR superfamily; especially TNFRSF19; DR3; OX40; and LTbeta receptor. RELT/TNFRSF19L is able to activate the NF-kappaB pathway and selectively binds tumor necrosis factor receptor-associated factor 1. RELT/TNFRSF19L is able to activate the NF-κB pathway and selectively binds tumor necrosis factor receptor-associated factor 1. Although the soluble form of RELT fusion protein does not inhibit the one-way mixed lymphocyte reaction; immobilized RELT/TNFRSF19L is capable of costimulating T-cell proliferation in the presence of CD3 signaling.

    Synonym: Tumor necrosis factor receptor superfamily member 19L; TNFRSF19L; Receptor expressed in lymphoid tissues; RELT

    分子量
    42 kDa
    NCBI登录号
    NP_116260
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