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REG3A Protein (Fc Tag)

REG3A 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7321167
发货至: 中国
  • 抗原 See all REG3A 蛋白
    REG3A (Regenerating Islet-Derived 3 alpha (REG3A))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 4
    • 4
    • 1
    大鼠
    资源
    • 6
    • 5
    • 4
    • 2
    • 2
    HEK-293 Cells
    标记
    This REG3A protein is labelled with Fc Tag.
    原理
    Recombinant Rat REG3A/HIP Protein (Fc Tag)
    序列
    Met1-Gln174
    产品特性
    A DNA sequence encoding the rat REG3A (BAA04904.1) (Met1-Gln174) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product REG3A 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    REG3A (Regenerating Islet-Derived 3 alpha (REG3A))
    别名
    REG3A/HIP (REG3A 产品)
    别名
    HIP Protein, HIP/PAP Protein, INGAP Protein, PAP Protein, PAP-H Protein, PAP1 Protein, PBCGF Protein, REG-III Protein, REG3 Protein, AV063448 Protein, Pap2 Protein, PapII Protein, PTP Protein, REG3G Protein, regenerating family member 3 alpha Protein, regenerating islet-derived 3 alpha Protein, REG3A Protein, Reg3a Protein
    背景

    Background: Regenerating islet-derived protein 3-alpha, also known as Regenerating islet-derived protein III-alpha, REG-3-alpha, REG3A, and HIP, is secreted protein which contains one C-type lectin domain. REG3A is constitutively expressed in intestine, and is a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It is overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. REG3A is also a stress protein involved in the control of bacterial proliferation. REG3A is down-regulated in most primary human gastric cancer cells, and might be useful in the diagnosis of gastric cancer. Additionally, REG3A is a target of beta-catenin signaling in Huh7 hepatoma cells. The REG1A and REG3A are downstream targets of the Wnt pathway during liver tumorigenesis.

    Synonym: REG3A,Pap2,Reg3

    分子量
    43.4 kDa
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