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RAMP3 Protein (Fc Tag)

RAMP3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317204
发货至: 中国
  • 抗原 See all RAMP3 蛋白
    RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    • 1
    • 1
    • 1
    资源
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This RAMP3 protein is labelled with Fc Tag.
    原理
    Recombinant Human RAMP3 Protein (Fc Tag)
    序列
    Met 1-Val118
    产品特性
    A DNA sequence encoding the human RAMP3 (Met1-Val118) was expressed with the Fc region of human IgG1 at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product RAMP3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))
    别名
    RAMP3 (RAMP3 产品)
    别名
    RAMP3 Protein, ramp3 Protein, AI850306 Protein, receptor activity modifying protein 3 Protein, receptor (G protein-coupled) activity modifying protein 3 Protein, Receptor activity-modifying protein 3 Protein, receptor (calcitonin) activity modifying protein 3 Protein, RAMP3 Protein, ramp3 Protein, Ramp3 Protein
    背景

    Background: RAMP3 belongs to the RAMP family. Members of this family are single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs have a wide biological distribution, high concentrations are found in the brain, lung, liver, heart and spleen with lower expression levels present in the testes, gastrointestinal tract and thyroid. RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. They are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of RAMP3 protein, CRLR functions as an adrenomedullin receptor.

    Synonym: RAMP3

    分子量
    37.8 kDa
    途径
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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