PRMT6 Protein (His tag,DYKDDDDK Tag)
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- 抗原 See all PRMT6 蛋白
- PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PRMT6 protein is labelled with His tag,DYKDDDDK Tag.
- 原理
- Recombinant Human PRMT6/HRMT1L6 Protein (His & FLAG Tag)
- 序列
- Met 1-Asp 375
- 产品特性
- A DNA sequence encoding the human PRMT6 (NP_060607.2) (Met 1-Asp 375) was expressed, fused with a polyhistidine tag at the C-terminus and the flag tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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- Discover our top product PRMT6 蛋白
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Protein Arginine Methyltransferase 6 (PRMT6) (AA 2-375) protein (His tag)
PRMT6 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Protein Arginine Methyltransferase 6 (PRMT6) (AA 1-316) protein (GST tag)PRMT6 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Protein Arginine Methyltransferase 6 (PRMT6) (AA 241-316) protein (GST tag)PRMT6 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Protein Arginine Methyltransferase 6 (PRMT6) (AA 1-375) protein (Strep Tag)Crystallography grade PRMT6 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Protein Arginine Methyltransferase 6 (PRMT6) (AA 1-378) protein (Strep Tag)Crystallography grade PRMT6 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Protein Arginine Methyltransferase 6 (PRMT6) protein (DYKDDDDK Tag)PRMT6 宿主: 人 宿主: Baculovirus Recombinant EAA, ScA
Protein Arginine Methyltransferase 6 (PRMT6) protein (Myc-DYKDDDDK Tag)PRMT6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))
- 别名
- PRMT6/HRMT1L6 (PRMT6 产品)
- 别名
- CG9927 Protein, DART6 Protein, Dmel\\CG9927 Protein, PRMT6 Protein, HRMT1L6 Protein, ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 6 Protein, ATPRMT6 Protein, protein arginine methyltransferase 6 Protein, DKFZp459B1431 Protein, Hrmt1l6 Protein, hrmt1l6 Protein, hrmt6 Protein, im:6908706 Protein, AW124876 Protein, BB233495 Protein, Arginine methyltransferase 6 Protein, protein arginine methyltransferase 6 Protein, protein arginine methyltransferase 6 S homeolog Protein, arginine N-methyltransferase, type I Protein, protein arginine N-methyltransferase 6 Protein, Art6 Protein, PRMT6 Protein, prmt6.S Protein, prmt6 Protein, Prmt6 Protein
- 背景
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Background: Protein arginine N-methyltransferase 6, also known as Histone-arginine N-methyltransferase PRMT6, PRMT6, and HRMT1L6, is a member of the protein arginine N-methyltransferase family and PRMT6 subfamily. PRMT6 is highly expressed in kidney and testes. PRMT6 is known to catalyze the generation of asymmetric dimethylarginine in polypeptides. It has been implicated in human immunodeficiency virus pathogenesis, DNA repair, and transcriptional regulation. PRMT6 is known to methylate histone H3 Arg-2 (H3R2), and this negatively regulates the lysine methylation of H3K4 resulting in gene repression. PRMT6 plays a key role in coupling process by functioning as a transcriptional coactivator that can regulate alternative splicing. PRMT6 coactivates the progesterone, glucocorticoid and oestrogen receptors in luciferase reporter assays in a hormone-dependent manner. Small interfering RNA (siRNA) oligonucleotide duplex knockdown of PRMT6 disrupts oestrogen-stimulated transcription of endogenous GREB1 and progesterone receptor in MCF-7 breast cancer cells. Neutralizing the activity of PRMT6 could inhibit tumor progression and may be of cancer therapeutic significance.
Synonym: HRMT1L6
- 分子量
- 44.4 kDa
- NCBI登录号
- NP_060607
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