PDCD4 Protein (His tag)
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- 抗原 See all PDCD4 蛋白
- PDCD4 (Programmed Cell Death 4 (PDCD4))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This PDCD4 protein is labelled with His tag.
- 原理
- Recombinant Human PDCD4/H731 Protein (His Tag)
- 序列
- Lys212-Pro357
- 产品特性
- Recombinant Human Programmed Cell Death Protein 4 is produced by our E.coli expression system and the target gene encoding Lys212-Pro357 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PDCD4 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PDCD4 (Programmed Cell Death 4 (PDCD4))
- 别名
- PDCD4/H731 (PDCD4 产品)
- 别名
- H731 Protein, D19Ucla1 Protein, Ma3 Protein, Tis Protein, Dug Protein, cb45 Protein, pdcd4 Protein, sb:cb45 Protein, wu:fc84b08 Protein, h731 Protein, MGC69337 Protein, PDCD4 Protein, wu:fa55g03 Protein, wu:fb08a11 Protein, wu:fe01a02 Protein, zgc:66311 Protein, programmed cell death 4 Protein, programmed cell death 4b Protein, programmed cell death 4 L homeolog Protein, programmed cell death 4 (neoplastic transformation inhibitor) Protein, programmed cell death 4a Protein, PDCD4 Protein, Pdcd4 Protein, pdcd4b Protein, pdcd4.L Protein, pdcd4 Protein, pdcd4a Protein
- 背景
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Background: Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation initiation and cap-dependent translation.PDCD4 promotes colonic neoplastic transformation and tumor invasion. PDCD4 is an important target for microrna R-21 in breast cancer cells. Shortage of PDCD4 expression is associated with colorectal cancer. Overexpression of PDCD4 in carcinoid cells results in inhibition of cell proliferation.
Synonym: Programmed Cell Death Protein 4, Neoplastic Transformation Inhibitor Protein, Nuclear Antigen H731-Like, Protein 197/15a, PDCD4, H731
- 分子量
- 17.0 kDa
- UniProt
- Q53EL6
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