PVRL1 Protein (His tag)
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- 抗原 See all PVRL1 蛋白
- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This PVRL1 protein is labelled with His tag.
- 原理
- Recombinant Human CD111/Nectin-1 Protein (His Tag)
- 序列
- Gln31-Thr334
- 产品特性
- Recombinant Human Poliovirus Receptor-Related Protein 1 is produced by our Mammalian expression system and the target gene encoding Gln31-Thr334 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PVRL1 蛋白
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Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 31-334) protein (His-Avi Tag)
PVRL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 31-334) protein (His-Avi Tag,Biotin)PVRL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 31-334) (Active) protein (Fc Tag)PVRL1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 1-352) protein (GST tag)PVRL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 33-142) protein (GST tag)PVRL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) protein (His tag)PVRL1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) protein (Fc Tag)PVRL1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
- 别名
- CD111/Nectin-1 (PVRL1 产品)
- 别名
- CD111 Protein, CLPED1 Protein, ED4 Protein, HIgR Protein, HVEC Protein, OFC7 Protein, PRR Protein, PRR1 Protein, PVRR Protein, PVRR1 Protein, SK-12 Protein, nectin-1 Protein, prr1 Protein, PVRL1 Protein, pvrl1 Protein, AI835281 Protein, AW549174 Protein, Cd111 Protein, HveC Protein, cd111 Protein, cd112 Protein, clped1 Protein, ed4 Protein, higr Protein, hveb Protein, hvec Protein, nectin-2 Protein, ofc7 Protein, prr Protein, prr2 Protein, pvrl2 Protein, pvrl2.L Protein, pvrr Protein, pvrr1 Protein, pvrr2 Protein, sk-12 Protein, nectin cell adhesion molecule 1 Protein, nectin-1 Protein, Poliovirus receptor-related protein 1 Protein, poliovirus receptor-related 1 (herpesvirus entry mediator C) Protein, nectin cell adhesion molecule 2 L homeolog Protein, NECTIN1 Protein, LOC100145553 Protein, pvrl1 Protein, nectin1 Protein, Nectin1 Protein, PVRL1 Protein, nectin2.L Protein
- 背景
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Background: Nectin-1 is a type I transmembrane glycoprotein belonging to the Ig superfamily. Nectin-1 promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between Nectin-1 and Nectin-3 and between Nectin-1 and Nectin-4. Nectin ECDs contain three Ig like domains: an N terminal V type that mediates ligand binding, and two C2 type. Nectin-1 binds viral Glycoprotein D to mediate Herpesvirus (but not Poxvirus) entry into vaginal mucosa, sensory neurons and fibroblasts. In forming adherens junctions and synapses, Nectin-1 and Nectin-3 initiate cell-cell interactions, recruiting αvβ3 integrin extracellularly and cadherins intracellularly through afadin and other junctional proteins. These interactions organize the cytoskeleton, strengthen attachment to basement membrane and promote further cell-cell connections. Nectin-1 and Nectin-3 have been found to localize assymetrically along the chemical synapse, with Nectin-1 primarily on the axonal side and Nectin-3 on the dendritic side. Deficiency of Nectin-1 can result in cleft lip/palate ectodermal dysplasia. Nectin-1 downregulation in epithelial cancers is mediated in part by ectodomain shedding, but it may contribute to invasiveness.
Synonym: Poliovirus Receptor-Related Protein 1, Herpes Virus Entry Mediator C, Herpesvirus Entry Mediator C, HveC, Herpesvirus Ig-Like Receptor, HIgR, Nectin-1, CD111, PVRL1, HVEC, PRR1,ED4,HIgR,HV1S,HVEC,nectin-1,OFC7,PRR,PVRR,PVRR1,SK-12
- 分子量
- 35.0 kDa
- UniProt
- Q15223
- 途径
- Cell-Cell Junction Organization
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