PLTP Protein (His tag)
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- 抗原 See all PLTP 蛋白
- PLTP (Phospholipid Transfer Protein (PLTP))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PLTP protein is labelled with His tag.
- 原理
- Recombinant Human PLTP Protein (His Tag)
- 序列
- Met 1-Val 493
- 产品特性
- A DNA sequence encoding the human PLTP isoform 1 (P55058-1) (Met 1-Val 493) was expressed, fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 80 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PLTP 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PLTP (Phospholipid Transfer Protein (PLTP))
- 别名
- PLTP (PLTP 产品)
- 别名
- zgc:100903 Protein, MGC84445 Protein, PLTP Protein, hdlcq9 Protein, DKFZp469A1437 Protein, BPIFE Protein, HDLCQ9 Protein, Bpife Protein, OD107 Protein, phospholipid transfer protein Protein, phospholipid transfer protein S homeolog Protein, PLTP Protein, pltp Protein, pltp.S Protein, LOC542343 Protein, Pltp Protein
- 背景
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Background: Phospholipid transfer protein, also known as Lipid transfer protein II and PLTP, is a secreted protein which belongs to the BPI/LBP/Plunc superfamily and BPI / LBP family. PLTP is nearly ubiquitously expressed in cells and tissues. PLTP converts HDL into larger and smaller particles. It may play a key role in extracellular phospholipid transport and modulation of hdl particles. High-density lipoproteins (HDL) play a major protective role against the development of coronary artery disease. PLTP is a main factor regulating the size and composition of HDL in the circulation and plays an important role in controlling plasma HDL levels. This is achieved via both the phospholipid transfer activity of PLTP and its capability to cause HDL conversion. PLTP is one of the key lipid transfer proteins in plasma and cerebrospinal fluid. It is involved in novel intracellular functions. PLTP is an important modulator of lipoprotein metabolism, including interparticle phospholipid transfer, remodeling of HDL, cholesterol and phospholipid efflux from peripheral tissues, and the production of hepatic VLDL. PLTP also plays an important role in inflammation and oxidative stress. Accordingly, PLTP has also been implicated in the development of atherosclerosis.
Synonym: BPIFE;HDLCQ9
- 分子量
- 54.5 kDa
- 途径
- Lipid Metabolism
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