PLA2G1B Protein (His tag)
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- 抗原 See all PLA2G1B 蛋白
- PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PLA2G1B protein is labelled with His tag.
- 原理
- Recombinant Human PLA2G1B/PLA2 Protein (His Tag)(Active)
- 序列
- Met 1-Ser 148
- 产品特性
- A DNA sequence encoding the human PLA2G1B (NP_000919.1) (Met 1-Ser 148) with a C-terminal polyhistidine tag was expressed.
- 纯度
- > 92 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to hydrolyze 1-Hexadecanoyl-2-(1-pyrenedecanoyl)-sn-glycero-3-phosphomethanol.The specific activity is >2,500 pmol/min/μg.
- Top Product
- Discover our top product PLA2G1B 蛋白
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Phospholipase A2, Group IB (PLA2G1B) (AA 23-146) protein (Fc Tag)
PLA2G1B 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Phospholipase A2, Group IB (PLA2G1B) (AA 23-148) protein (Fc Tag)PLA2G1B 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Phospholipase A2, Group IB (PLA2G1B) (AA 23-148) protein (His tag)PLA2G1B 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Phospholipase A2, Group IB (PLA2G1B) (AA 17-70) protein (GST tag)PLA2G1B 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Phospholipase A2, Group IB (PLA2G1B) (AA 23-148) protein (His tag)Crystallography grade PLA2G1B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Phospholipase A2, Group IB (PLA2G1B) (AA 23-146) protein (His tag)Crystallography grade PLA2G1B 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Phospholipase A2, Group IB (PLA2G1B) protein (Myc-DYKDDDDK Tag)PLA2G1B 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 10 mM Tris, 5 mM CaCl2, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))
- 别名
- PLA2G1B/PLA2 (PLA2G1B 产品)
- 别名
- C133 Protein, CG4346 Protein, Dmel\\CG42237 Protein, Dmel_CG4346 Protein, PLA2 Protein, GB13351 Protein, bvPLA2 Protein, PLA2A Protein, PPLA2 Protein, sPLA(2)-IB Protein, Pla2a Protein, sPLA2IB Protein, PLA2G1B Protein, CG42237 gene product from transcript CG42237-RB Protein, phospholipase A2 Protein, phospholipase A2 group IB Protein, phospholipase A2, group IB, pancreas Protein, phospholipase A2 group IVA Protein, CG42237 Protein, PLA2 Protein, LOC100631065 Protein, Pla2 Protein, PLA2G1B Protein, Pla2g1b Protein, PLA2G4A Protein
- 背景
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Background: phospholipase A2, also known as Phosphatidylcholine 2-acylhydrolase 1B, Group IB phospholipase A2, PLA2 and PLA2G1B, is a secreted protein which belongs to the phospholipase A2 family. Phospholipase A2 / PLA2G1B catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic Phospholipase A2 / PLA2G1B enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of Phospholipase A2 / PLA2G1B have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets. Mice lacking in Phospholipase A2 / PLA2G1B are resistant to obesity and diabetes induced by feeding a diabetogenic high-fat/high-carbohydrate diet. Oral supplementation of a diabetogenic diet with the PLA2G1B inhibitor methyl indoxam effectively suppresses diet-induced obesity and diabetes. PLA2G1B inhibition may be a potentially effective oral therapeutic option for treatment of obesity and diabetes.
Synonym: PLA2G1B;Phospholipase A2;Group IB phospholipase A2;PLA2;PLA2A;PPLA2
- 分子量
- 16.2 kDa
- NCBI登录号
- NP_000919
- 途径
- Inositol Metabolic Process, VEGF Signaling
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