PDE1C Protein (GST tag,His tag)
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- 抗原 See all PDE1C 蛋白
- PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This PDE1C protein is labelled with GST tag,His tag.
- 原理
- Recombinant Human PDE1C Protein (His & GST Tag)
- 序列
- Met 1-Glu634
- 产品特性
- A DNA sequence encoding the human PDE1C (Q8TAE4) (Met1-Glu634) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 纯度
- > 85 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PDE1C 蛋白
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phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C) (AA 1-709) protein (Strep Tag)
Crystallography grade PDE1C 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C) (AA 1-706) protein (Strep Tag)Crystallography grade PDE1C 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C) protein (His tag)PDE1C 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol, 3 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
- 别名
- PDE1C (PDE1C 产品)
- 别名
- CG14940 Protein, CG14942 Protein, CG14943 Protein, CG14944 Protein, CG31757 Protein, CG31758 Protein, CG42325 Protein, CG44007 Protein, Dmel\\CG44007 Protein, Dmel_CG14940 Protein, Dmel_CG14943 Protein, Dmel_CG14944 Protein, Dmel_CG31757 Protein, Dmel_CG31758 Protein, Dmel_CG42325 Protein, PDE1C Protein, PDE1c Protein, GB13690 Protein, Hcam3 Protein, Phosphodiesterase 1c Protein, phosphodiesterase 1C Protein, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Protein, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C Protein, phosphodiesterase 1C, calmodulin-dependent b Protein, Pde1c Protein, PDE1C Protein, LOC724389 Protein, LOC100019026 Protein, pde1cb Protein
- 背景
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Background: PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDEs are expressed ubiquitously, with each subtype having a specific tissue distribution. These enzymes are involved in many signal transduction pathways and their functions include vascular smooth muscle proliferation and contraction, cardiac contractility, platelet aggregation, hormone secretion, immune cell activation, and they are involved in learning and memory. PDE1C has a high affinity for both cAMP and cGMP. It is expressed in several tissues, including brain and heart. As a cyclic nucleotide phosphodiesterase, PDE1C has a dual-specificity for the second messengers cAMP and cGMP.
Synonym: cam-PDE1C,hCam-3,Hcam3
- 分子量
- 100 kDa
- UniProt
- Q8TAE4
- 途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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