PIP4K2A Protein (His tag)
-
- 抗原 See all PIP4K2A 蛋白
- PIP4K2A (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 人细胞
- 标记
- This PIP4K2A protein is labelled with His tag.
- 原理
- Recombinant Human PIP4K2A Protein (His Tag)
- 序列
- Met 1-Thr406
- 产品特性
- Recombinant Human Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha is produced by our Mammalian expression system and the target gene encoding Met1-Thr406 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PIP4K2A 蛋白
-
Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A) (AA 208-406) protein (His-IF2DI Tag)
PIP4K2A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A) (AA 1-406) protein (GST tag)PIP4K2A 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A) (AA 304-365) protein (GST tag)PIP4K2A 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A) (AA 2-406) protein (His tag)Crystallography grade PIP4K2A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A) (AA 2-405) protein (His tag)Crystallography grade PIP4K2A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A) protein (Myc-DYKDDDDK Tag)PIP4K2A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- PIP4K2A (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A))
- 别名
- PIP4K2A (PIP4K2A 产品)
- 别名
- PI5P4KA Protein, PIP5K2A Protein, PIP5KII-alpha Protein, PIP5KIIA Protein, PIPK Protein, AW742916 Protein, Pip5k2a Protein, pipk Protein, pi5p4ka Protein, pip5k2a Protein, pip5kiia Protein, pip4k2a Protein, zgc:194746 Protein, zgc:194777 Protein, phosphatidylinositol-5-phosphate 4-kinase type 2 alpha Protein, phosphatidylinositol-5-phosphate 4-kinase, type II, alpha Protein, phosphatidylinositol-5-phosphate 4-kinase, type II, alpha S homeolog Protein, phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a Protein, PIP4K2A Protein, Pip4k2a Protein, pip4k2a.S Protein, pip4k2a Protein, pip4k2aa Protein
- 背景
-
Background: Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PIP4K2A) is a member of the phosphatidylinositol-4-phosphate 5-kinase family. It contains 1 PIPK domain and is expressed ubiquitously, with high levels in the brain. It catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). It may exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. It may regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation, negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P. It also involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size.
Synonym: 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha,Diphosphoinositide kinase 2-alpha,PIP5KIII,Phosphatidylinositol 5-phosphate 4-kinase type II alpha,PtdIns(4)P-5-kinase B isoform,PtdIns(4)P-5-kinase C isoform,PtdIns(5)P-4-kinase isoform 2-alpha
- 分子量
- 47.3 kDa
- UniProt
- P48426
- 途径
- Inositol Metabolic Process
-
