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Peroxiredoxin 2 Protein (PRDX2) (His tag)

PRDX2 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 92 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7317603
发货至: 中国
  • 抗原 See all Peroxiredoxin 2 (PRDX2) 蛋白
    Peroxiredoxin 2 (PRDX2)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 11
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 15
    • 6
    • 2
    • 1
    Baculovirus infected Insect Cells
    标记
    This Peroxiredoxin 2 protein is labelled with His tag.
    原理
    Recombinant Human Peroxiredoxin 2/PRDX2 Protein (His Tag)(Active)
    序列
    Met 1-Asn 198
    产品特性
    A DNA sequence encoding the human PRDX2 (P32119) (Met 1-Asn 198) was expressed, with a polyhistidine tag at the N-terminus.
    纯度
    > 92 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to reduce H2O2.The specific activity is >300 pmoles/min/μg.
    Top Product
    Discover our top product PRDX2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 10 % glycerol
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Peroxiredoxin 2 (PRDX2)
    别名
    Peroxiredoxin 2/PRDX2 (PRDX2 产品)
    别名
    NKEF-B Protein, NKEFB Protein, PRP Protein, PRX2 Protein, PRXII Protein, PTX1 Protein, TDPX1 Protein, TPX1 Protein, TSA Protein, AL022839 Protein, Band-8 Protein, NkefB Protein, PrxII Protein, TDX1 Protein, TPx Protein, TPx-B Protein, TR Protein, Tdpx1 Protein, Torin Protein, nkefb Protein, prx-2 Protein, prx2 Protein, prxii Protein, tdpx1 Protein, tpx1 Protein, peroxiredoxin 2 Protein, peroxiredoxin 2 L homeolog Protein, PRDX2 Protein, Prdx2 Protein, prdx2.L Protein
    背景

    Background: Peroxiredoxin-2, also known as Natural killer cell-enhancing factor B, NKEF-B, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, PRDX2 and NKEFB, is a cytoplasm protein which belongs to the ahpC / TSA family. Peroxiredoxin-2 / PRDX2 contains one thioredoxin domain. Peroxiredoxin-2 / PRDX2 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-2 / PRDX2 is not able to receive electrons from glutaredoxin. It may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-2 / PRDX2 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The Peroxiredoxins / Prx are a family of peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins / Prx family is divided into six groups ( PRDX1,PRDX2, PRDX3, PRDX4, PRDX5, PRDX6 ) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins / Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins / Prx has a proliferative effect and may be related to cancer development or progression.

    Synonym: HEL-S-2a;NKEF-B;NKEFB;PRP;PRX2;PRXII;PTX1;TDPX1;TPX1;TSA

    分子量
    24 kDa
    UniProt
    P32119
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