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PDAP1 Protein (His tag)

PDAP1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318877
发货至: 中国
  • 抗原 See all PDAP1 蛋白
    PDAP1 (PDGFA Associated Protein 1 (PDAP1))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    资源
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This PDAP1 protein is labelled with His tag.
    原理
    Recombinant Human PDAP1/PAP Protein (His Tag)
    序列
    Met 1-Lys181
    产品特性
    Recombinant Human PDGF-Associated Protein is produced by our E.coli expression system and the target gene encoding Met1-Lys181 is expressed with a 6His tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PDAP1 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM Tris, 100 mM NaCl, 0.1 mM PMSF, 2 mM DTT, pH 8.0.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    PDAP1 (PDGFA Associated Protein 1 (PDAP1))
    别名
    PDAP1/PAP (PDAP1 产品)
    别名
    pdap1 Protein, zgc:56213 Protein, HASPP28 Protein, PAP Protein, PAP1 Protein, Haspp28 Protein, pdgfa associated protein 1b Protein, 28 kDa heat- and acid-stable phosphoprotein Protein, PDGFA associated protein 1 Protein, pdap1b Protein, CpipJ_CPIJ013582 Protein, PDAP1 Protein, Pdap1 Protein
    背景

    Background: Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDGF-Associated Protein (PAP) is a phosphoprotein that may enhance PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha.

    Synonym: 28 kDa Heat- and Acid-Stable Phosphoprotein, PDGF-Associated Protein, PAP, PDGFA-Associated Protein 1, PAP1, PDAP1, HASPP28

    分子量
    22.8 kDa
    UniProt
    Q13442
    途径
    Platelet-derived growth Factor Receptor Signaling
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